SCHEMBL1885602

SCHEMBL1885602

Cc1cc2ccccc2n1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.55
TSHR P16473 2/20 0.55
MAPK1 P28482 2/20 0.48
HTT P42858 1/20 0.48
NOTUM Q6P988 1/20 0.46
KDM4E B2RXH2 4/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
ATM Q13315 1/20 0.45
KMT2A Q03164 4/20 0.44
HPGD P15428 2/20 0.44
MEN1 O00255 2/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HSD17B10 Q99714 1/20 0.44
CYP19A1 P11511 1/20 0.43
GAA P10253 1/20 0.43
SLC6A2 P23975 1/20 0.41
MAPT P10636 2/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30446730 1.00 ALDH1A1 (0.55) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL13425012 0.94 ALDH1A1 (0.47) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL64405 0.90 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL13483671 0.89 TSHR (0.43) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL13241999 0.89 APP (0.46) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL12345965 0.88 ALDH1A1 (0.43) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL26192196 0.85 MAPK1 (0.50) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL715063 0.85 ALDH1A1 (0.41) ALDH1A1TSHRMAPK1HTTNOTUM
SCHEMBL6986420 0.85 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1HTTKDM4E
SCHEMBL76833 0.85 ESR2 (0.47) ALDH1A1TSHRNOTUMKDM4EKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230242557-A9 PROTEASOME ACTIVITY ENHANCING COMPOUNDS Kineta, Inc. 2023-08-03 US disclosed
US-20230183256-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS YUMANITY THERAPEUTICS, INC. 2023-06-15 US disclosed
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-01 US disclosed
US-11121328-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-09-14 US disclosed
US-20200403167-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays NATIONAL SCIENCE FOUNDATION 2020-12-24 US disclosed
US-10804476-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-10-13 US disclosed
CN-109453816-B Catalyst for olefin hydroformylation reaction and preparation method and application thereof 四川大学 2020-08-25 CN disclosed
US-20190263841-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-08-29 US disclosed
WO-2019115423-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-06-20 WO disclosed
WO-2019101719-A1 MATERIALS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-05-31 WO disclosed
US-20070190355-A1 Material for organic electroluminescence device and organic electroluminescence device utilizing the same IDEMITSU KOSAN CO., LTD (JP) 2007-08-16 US disclosed
US-20070123707-A1 Nitrogen-containing monodentate phosphines and their use in catalysis DEGUSSA AG (DE) 2007-05-31 US disclosed
US-20070088166-A1 Clickphosphines for transition metal-catalyzed reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-04-19 US disclosed
US-20070009760-A1 Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device INOUE TETSUYA 2007-01-11 US disclosed
US-20070009760-A1 Coordination metal compound, material for organic electroluminescence device, material for luminescent coating formation and organic electroluminescence device INOUE TETSUYA 2007-01-11 US disclosed
EP-1666440-A1 METHOD FOR PRODUCING AROMATIC UNSATURATED COMPOUND Sumitomo Chemical Company, Limited (JP) 2006-06-07 EP disclosed
US-4771032-A PHOTODECOMPOSING COLORING COMPONENTS COMPRISING A DIAZO COMPOUND AND COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1988-09-13 US disclosed
US-4758495-A Diazo microcapsule recording material prepared using ion exchange treatment FUJI PHOTO FILM CO., LTD. (JP) 1988-07-19 US disclosed
US-4737484-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-04-12 US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11121328-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays DPYD, PAICS, PDCD11 ALDH1A1 1028/4885TSHR 3189/4885MAPK1 4326/4885
US-20230242557-A9 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PSMG3, PSMB1, PSMC1 ALDH1A1 3439/4885TSHR 4381/4885MAPK1 2013/4885
US-20230172057-A1 HETEROCYCLIC COMPOUND CONTAINING HETEROATOM SUBSTITUTED FLUORENE AND OPTOELECTRONIC DEVICE CHRM1, CHRM2, CHRM4 ALDH1A1 3072/4885TSHR 595/4885MAPK1 1222/4885
US-20200403167-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays DPYD, PAICS, PDCD11 ALDH1A1 1028/4885TSHR 3189/4885MAPK1 4326/4885
US-20190263841-A1 COMPOUNDS FOR ELECTRONIC DEVICES ETV6, EED, FES ALDH1A1 636/4885TSHR 3106/4885MAPK1 2169/4885
US-20070123707-A1 Nitrogen-containing monodentate phosphines and their use in catalysis HDHD5, PNP, PHOSPHO1 ALDH1A1 3129/4885TSHR 3705/4885MAPK1 1734/4885
US-20070088166-A1 Clickphosphines for transition metal-catalyzed reactions WEE1, WEE2, ITK ALDH1A1 2744/4885TSHR 1041/4885MAPK1 1586/4885
US-10804476-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays DPYD, PAICS, PDCD11 ALDH1A1 1028/4885TSHR 3189/4885MAPK1 4326/4885
US-20230183256-A1 PROTEASOME ACTIVITY ENHANCING COMPOUNDS PSMG3, PSME3, PSMC4 ALDH1A1 3438/4885TSHR 3977/4885MAPK1 2572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.