Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA9 | Q16790 | 2/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.56 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.56 |
| ▸ | MMP1 | P03956 | 2/20 | 0.56 |
| ▸ | MMP2 | P08253 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | MMP3 | P08254 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12707436 | 0.81 | NPC1 (0.55) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL6160040 | 0.80 | HDAC3 (0.55) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL1756655 | 0.80 | CA12 (0.63) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL4831685 | 0.80 | PLAAT5 (0.70) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL426275 | 0.80 | CA12 (0.63) | CA12CA2CA9EPHX1PLAAT5 | |
| Phenethylcarbamic Acid SCHEMBL249525 | 0.79 | CA12 (0.68) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL22412530 | 0.79 | PLAAT5 (0.75) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL6032606 | 0.79 | EPHX1 (0.85) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL1027805 | 0.79 | SMN1; SMN2 (0.64) | CA12CA2CA9EPHX1PLAAT5 | |
| SCHEMBL31598579 | 0.78 | PLAAT5 (0.62) | CA12CA2CA9EPHX1PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080381-B1 | HIGH REFRACTIVE INDEX OPHTHALMIC DEVICE MATERIALS PREPARED USING A POST-POLYMERIZATION CROSS-LINKING METHOD | ALCON MFG LTD (US) | 2005-07-27 | — | — | EP | claimed |
| EP-1002244-B1 | METHOD OF PREPARING FOLDABLE HIGH REFRACTIVE INDEX ACRYLIC OPHTHALMIC DEVICE MATERIALS | ALCON LAB INC (US) | 2003-02-26 | — | — | EP | claimed |
| EP-1079870-B1 | BICOMPOSITE INTRAOCULAR LENS AND METHOD FOR ITS PREPARATION | ALCON LAB INC (US) | 2001-11-14 | — | — | EP | claimed |
| EP-1071482-B1 | INTRAOCULAR LENS COATING COMPOSITIONS | ALCON LAB INC (US) | 2001-10-04 | — | — | EP | claimed |