Phenethylcarbamic Acid

Phenethylcarbamic Acid

SCHEMBL249525

O=C(O)NCCc1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.68
CA2 P00918 2/20 0.68
CA9 Q16790 2/20 0.68
EPHX1 P07099 1/20 0.66
PLAAT5 Q96KN8 3/20 0.63
PLAAT4 Q9UL19 3/20 0.63
MMP1 P03956 2/20 0.63
MMP2 P08253 2/20 0.63
CA1 P00915 1/20 0.63
MMP3 P08254 1/20 0.63
NPC1 O15118 4/20 0.63
RAB9A P51151 4/20 0.63
SMN1; SMN2 Q16637 3/20 0.63
ALDH1A1 P00352 2/20 0.61
TAAR1 Q96RJ0 1/20 0.61
HDAC2 Q92769 2/20 0.59
HDAC8 Q9BY41 2/20 0.59
HDAC6 Q9UBN7 2/20 0.59
PLAAT3 P53816 2/20 0.59
PLAAT2 Q9NWW9 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenethylcarbamic Acid SCHEMBL9718519 0.98 CA12 (0.66) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL4459966 0.98 CA12 (0.66) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL28010696 0.98 CA12 (0.66) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL28203613 0.96 CA12 (0.63) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL28210162 0.94 CA12 (0.61) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL11405970 0.92 EPHX1 (0.73) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL12478843 0.90 SMN1; SMN2 (0.59) CA12CA2CA9EPHX1PLAAT5
Phenethylcarbamic Acid SCHEMBL28147202 0.90 CA12 (0.58) CA12CA2CA9EPHX1PLAAT5
SCHEMBL1728418 0.88 CNR1 (0.59) CA12CA2CA9EPHX1PLAAT5
SCHEMBL164622 0.87 L3MBTL1 (0.72) EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3715346-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2024-01-03 EP claimed
EP-2970107-B1 PHOTOSWITCHABLE HDAC INHIBITORS MASSACHUSETTS GEN HOSPITAL (US) 2023-11-15 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
CN-112851671-B 4-substituted pyrido [2,3-d ] pyrimidine-7-ketone compound and preparation method and application thereof 南京思聚生物医药有限公司 2022-03-29 CN claimed
EP-3172213-B1 MACROCYCLIC KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2021-09-22 EP claimed
EP-3092220-B1 VITAMIN C PRODRUGS AND USES THEREOF UNIV FLORIDA (US) 2021-01-20 EP claimed
EP-3171874-B1 IMIDAZOLYL KINASE INHIBITORS AND USES THEREOF DANA FARBER CANCER INST INC (US) 2020-11-18 EP claimed
US-20200331860-A1 C-Met Modulators and Methods of Use EXELIXIS INC (US) 2020-10-22 US claimed
EP-2016044-B1 PENTACYCLINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS HARVARD COLLEGE (US) 2020-06-10 EP claimed
US-6500835-B2 FOR PROPHYLAXIS AND THERAPY OF FIBROSIS INVOLVING EXTRACELLULAR MATRIX DYSBOLISM HAVING A CHYMASE INHIBITOR AS AN EFFECTIVE INGREDIENT; SIDE EFFECT REDUCTION SUNTORY LIMITED (JP) 2002-12-31 US claimed
WO-2002098850-A2 CHEMICAL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS AS CATHEPSIN S INHIBITORS AXYS PHARMACEUTICALS, INC. (US) 2002-12-12 WO claimed
EP-1070076-A4 CHIRAL SEPARATIONS OF PYRIMIDINES CHIRAL TECHNOLOGIES INC (US) 2002-05-29 EP claimed
US-6239175-B1 Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM P.L.C. (GB) 2001-05-29 US claimed
WO-2001034573-A1 COMPOUNDS ASTRAZENECA AB (SE) 2001-05-17 WO claimed
EP-1070076-A1 CHIRAL SEPARATIONS OF PYRIMIDINES Chiral Technologies, Inc. (US) 2001-01-24 EP claimed
WO-1999047531-A1 CHIRAL SEPARATIONS OF PYRIMIDINES CHIRAL TECHNOLOGIES, INC. (US) 1999-09-23 WO claimed
EP-0253372-B1 1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indoles, a process for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1994-09-28 EP claimed
EP-0085204-B1 PROCESS FOR THE CO-PRODUCTION OF CARBOXYLIC ACIDS AND CARBOXYLIC ACID ESTERS SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1986-02-12 EP claimed
EP-0031385-A1 PROCESS FOR PREPARING POLYMETHYLENEPOLYPHENYL POLYCARBAMATE MITSUI TOATSU CHEMICALS, Inc. (JP) 1981-07-08 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200331860-A1 C-Met Modulators and Methods of Use FLT4, FLT1, MET CA12 2958/4885CA2 1724/4885CA9 1962/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.