Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4801891 | 0.87 | CNR1 (0.45) | MAT2ACNR1CNR2PPARG | |
| SCHEMBL6437376 | 0.80 | CNR1 (0.45) | GAAHTTMAT2ACNR1CNR2 | |
| SCHEMBL4808021 | 0.78 | CNR1 (0.43) | CNR1CNR2PPARG | |
| SCHEMBL4807346 | 0.74 | CNR1 (0.44) | MAT2ACNR1CNR2NPSR1 | |
| SCHEMBL4804629 | 0.70 | CNR1 (0.56) | CNR1CNR2ALDH1A1MAPTHPGD | |
| SCHEMBL4808039 | 0.70 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL4807100 | 0.69 | CNR1 (0.47) | CNR1CNR2 | |
| SCHEMBL4807322 | 0.69 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL6454643 | 0.68 | CNR1 (0.33) | CNR1CNR2 | |
| SCHEMBL4807155 | 0.68 | CNR1 (0.46) | MAT2ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546115-A2 | SUBSTITUTED PYRIMIDINES | Merck & Co., Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029204-A2 | SUBSTITUTED PYRIMIDINES | MERCK & CO., INC. (US) | 2004-04-08 | — | — | WO | disclosed |