Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CACNB4 | O00305 | 4/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 4/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 4/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 4/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.33 |
| ▸ | CACNB3 | P54284 | 4/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 4/20 | 0.33 |
| ▸ | CACNG7 | P62955 | 4/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 4/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 4/20 | 0.33 |
| ▸ | CACNG1 | Q06432 | 4/20 | 0.33 |
| ▸ | CACNB2 | Q08289 | 4/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 4/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.33 |
| ▸ | CACNA1E | Q15878 | 4/20 | 0.33 |
| ▸ | CACNA2D4 | Q7Z3S7 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809553 | 0.85 | CNR1 (0.46) | CNR1CNR2 | |
| SCHEMBL4805178 | 0.73 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL4807832 | 0.70 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL4807053 | 0.70 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL4801677 | 0.68 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL6440656 | 0.68 | GAA (0.36) | CNR1CNR2 | |
| SCHEMBL4807617 | 0.67 | PTGS2 (0.38) | CNR1CNR2 | |
| SCHEMBL4800838 | 0.67 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL6437376 | 0.64 | CNR1 (0.45) | CNR1CNR2 | |
| SCHEMBL4808245 | 0.62 | CNR1 (0.53) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546115-A2 | SUBSTITUTED PYRIMIDINES | Merck & Co., Inc. (US) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004029204-A2 | SUBSTITUTED PYRIMIDINES | MERCK & CO., INC. (US) | 2004-04-08 | — | — | WO | disclosed |