Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 8/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959903 | 0.83 | KMT2A (0.40) | KMT2AESR1ALDH1A1LIMK1MAPK14 | |
| SCHEMBL27556606 | 0.81 | TNKS (0.41) | KMT2AALDH1A1KDM4EMAPTKDR | |
| SCHEMBL5192672 | 0.77 | ESR1 (0.49) | KMT2AESR1ALDH1A1LIMK1MAPK14 | |
| SCHEMBL7738310 | 0.75 | FLT1 (0.34) | ESR1ALDH1A1LIMK1CDK8ROCK1 | |
| SCHEMBL8190241 | 0.75 | CLK4 (0.49) | ALDH1A1LIMK1MAPTTDP1CDK8 | |
| SCHEMBL14465345 | 0.75 | NPC1 (0.60) | ALDH1A1KDM4EMAPTTDP1KDR | |
| SCHEMBL6599436 | 0.75 | CLK4 (0.47) | KMT2AALDH1A1KDM4EMAPTTDP1 | |
| SCHEMBL5533567 | 0.74 | ESR1 (0.46) | KMT2AESR1ALDH1A1LIMK1MAPK14 | |
| SCHEMBL1263722 | 0.74 | ESR1 (0.50) | KMT2AESR1ALDH1A1LIMK1MAPK14 | |
| SCHEMBL19065614 | 0.74 | ESR1 (0.46) | KMT2AESR1ALDH1A1LIMK1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100374424-C | Heterocyclic amide derivative and use as pesticide | BAYER CROPSCIENCE AG (DE) | 2008-03-12 | — | — | CN | claimed |
| US-6869715-B2 | Ion conductive membrane for electrochemical application | GKSS-FORSCHUNGSZENTRUM GEESTHACHT, GMBH (DE) | 2005-03-22 | — | — | US | claimed |
| US-20040248958-A1 | Heterocyclic amide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-12-09 | — | — | US | claimed |
| CN-1551870-A | heterocyclic amide derivatives and their use as pesticides | 拜尔农作物科学股份公司 | 2004-12-01 | — | — | CN | claimed |
| US-20040101732-A1 | Ion conductive membrane for electrochemical application | GKSS FORSCHUNGSZENTRUM GEESTHACHT GMBH (DE) | 2004-05-27 | — | — | US | claimed |
| EP-1417178-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | claimed |
| WO-2003004464-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-16 | — | — | WO | claimed |
| CN-106456581-A | Trka kinase inhibitors, compositions and methods thereof | 默沙东公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-103442566-B | The compound of Therapeutic cancer | GTX, INC. (US) | 2015-12-09 | — | — | CN | disclosed |
| CN-103442566-A | Compounds for treatment of cancer | GTX INC | 2013-12-11 | — | — | CN | disclosed |
| CN-100374424-C | Heterocyclic amide derivative and use as pesticide | BAYER CROPSCIENCE AG (DE) | 2008-03-12 | — | — | CN | disclosed |
| US-20040248958-A1 | Heterocyclic amide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-12-09 | — | — | US | disclosed |
| CN-1551870-A | heterocyclic amide derivatives and their use as pesticides | 拜尔农作物科学股份公司 | 2004-12-01 | — | — | CN | disclosed |
| US-4956470-A | BACTERICIDES, FUNGICIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4814332-A | PARASITICIDES | HOFFMAN-LA ROCHE INC. (US) | 1989-03-21 | — | — | US | disclosed |
| US-4808727-A | CHEMICAL INTERMEDIATES FOR WATER-SOLUBLE SALTS OF PARASITICIDES | HOFFMANN-LAROCHE INC. (US) | 1989-02-28 | — | — | US | disclosed |
| CN-87107148-A | 1, the 3-Disubstituted imidazolium salts | — | 1988-05-18 | — | — | CN | disclosed |
| EP-0266532-A1 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-05-11 | — | — | EP | disclosed |
| EP-0253084-A2 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-20 | — | — | EP | disclosed |
| CN-87103528-A | 1, the 3-3-disubstituted imidazolium salts | — | 1987-12-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | DDT, CYP2E1, CYP1A1 | KMT2A 1254/4885ESR1 2199/4885ALDH1A1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.