Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 10/20 | 0.41 |
| ▸ | PRKACA | P17612 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27826039 | 0.81 | NISCH (0.38) | KDM4EALDH1A1MAPTTDP1KDR | |
| SCHEMBL5192672 | 0.77 | ESR1 (0.49) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL28219310 | 0.75 | ESR1 (0.32) | ESR1 | |
| SCHEMBL18419722 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL6440778 | 0.74 | KMT2A (0.50) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL4482636 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL19065614 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL1263722 | 0.74 | ESR1 (0.50) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL786747 | 0.74 | HDAC4 (0.52) | ESR1CHEK1LIMK1MAPK14KDM4E | |
| SCHEMBL5324352 | 0.74 | ESR1 (0.46) | ESR1CHEK1LIMK1MAPK14KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109438444-A | It a kind of imidazo [1,2- α] pyridine derivate, preparation method and its is applied in color-change powder | 上海甘田光学材料有限公司 | 2019-03-08 | — | — | CN | claimed |
| CN-102548991-B | Imidazopyridine or imidazopyrimidine derivatives as phosphodiesterase 10A inhibitors | HOFFMANN LA ROCHE | 2015-03-25 | — | — | CN | claimed |
| WO-2007126262-A1 | ANION RECEPTOR, AND ELECTROLYTE USING THE SAME | KYUNGWON ENTERPRISE CO., LTD. (KR) | 2007-11-08 | — | — | WO | claimed |
| CN-111004234-A | C3-site halogenation method of 2-phenylimidazo [1,2- α ] pyridine compound | 湖南农业大学 | 2020-04-14 | — | — | CN | disclosed |
| CN-110483505-A | 2- phenylimidazole [1,2-a] pyridine -3- nitrile replaced using DMF and ammonium iodide as cyanylation agent building | UNIV GUILIN TECHNOLOGY | 2019-11-22 | — | — | CN | disclosed |
| CN-110372694-A | A kind of new method of 2- phenylimidazole [1,2-a] pyridine -3- aldehyde replaced using DMF as formylation reagent building | 桂林理工大学 | 2019-10-25 | — | — | CN | disclosed |
| CN-110225912-A | GSK-3 inhibitor | 百时美施贵宝公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-108129478-B | A kind of copper process for catalytic synthesis of organic sulphones and application | 曲阜师范大学 | 2019-07-09 | — | — | CN | disclosed |
| CN-109438444-A | It a kind of imidazo [1,2- α] pyridine derivate, preparation method and its is applied in color-change powder | 上海甘田光学材料有限公司 | 2019-03-08 | — | — | CN | disclosed |
| CN-106866661-B | A kind of preparation method of cyanomethylation Imidazopyridine compound | 南京师范大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-109126875-A | A kind of carbon 60- bidentate N-heterocyclic carbine palladium (0) compound and its preparation method and application | 洛阳师范学院 | 2019-01-04 | — | — | CN | disclosed |
| CN-106928221-A | The method for synthesizing imidazoles fused heterocyclic compound | 首都师范大学 | 2017-07-07 | — | — | CN | disclosed |
| CN-105218540-B | A kind of preparation method of 3 thiocarbamoyl imidazoles of C simultaneously [1,2 a] pyridine compounds and their | 曲阜师范大学 | 2017-07-04 | — | — | CN | disclosed |
| CN-106866661-A | A kind of preparation method of cyanomethylation Imidazopyridine compound | 南京师范大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-105085520-B | 3 (2 nitro, 1 phenethyl) 2 (2 phenylimidazoles simultaneously [1,2 α] pyridine) class compound | 郑州大学 | 2017-03-29 | — | — | CN | disclosed |
| WO-2016045591-A1 | NOVEL IMIDAZOPYRIDAZINE COMPOUNDS AND THEIR USE | HUTCHISON MEDIPHARMA LIMITED (CN) | 2016-03-31 | — | — | WO | disclosed |
| CN-105218540-A | The preparation method of a kind of C-3 position thiocarbamoyl imidazole also [1,2-a] pyridine compounds and their | UNIV QUFU NORMAL | 2016-01-06 | — | — | CN | disclosed |
| CN-105085520-A | 3-(2-nitro-1-phenylethyl)-2-(2-phenyl-imidazo[1,2-alpha] pyridine) compound | UNIV ZHENGZHOU | 2015-11-25 | — | — | CN | disclosed |
| CN-102548991-B | Imidazopyridine or imidazopyrimidine derivatives as phosphodiesterase 10A inhibitors | HOFFMANN LA ROCHE | 2015-03-25 | — | — | CN | disclosed |
| WO-2007126262-A1 | ANION RECEPTOR, AND ELECTROLYTE USING THE SAME | KYUNGWON ENTERPRISE CO., LTD. (KR) | 2007-11-08 | — | — | WO | disclosed |