Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27556606 | 0.81 | TNKS (0.41) | ALDH1A1KDM4ERAB9ASMN1; SMN2HPGD | |
| SCHEMBL14675684 | 0.80 | CLK4 (0.48) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL5650614 | 0.79 | CLK4 (0.47) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL28851885 | 0.79 | CLK4 (0.47) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL6600060 | 0.78 | CCNB2 (0.47) | ALDH1A1KDM4ERAB9ASMN1; SMN2HPGD | |
| Hydrochloric Acid SCHEMBL28747737 | 0.77 | CLK4 (0.46) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL11771718 | 0.77 | KDR (0.49) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL6440778 | 0.75 | KMT2A (0.50) | CLK4ALDH1A1KDM4ERAB9AKMT2A | |
| SCHEMBL11026854 | 0.75 | CYP2C19 (0.47) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10981149 | 0.75 | ADRA2A (0.56) | CLK4ALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-12-09 | — | — | US | claimed |
| EP-1417178-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | claimed |
| WO-2003004464-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-16 | — | — | WO | claimed |
| US-20040248958-A1 | Heterocyclic amide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-12-09 | — | — | US | disclosed |
| EP-1417178-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | Bayer CropScience AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003004464-A2 | HETEROCYCLIC AMIDE DERIVATIVES AND THE USE THEREOF AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-16 | — | — | WO | disclosed |
| US-4956470-A | BACTERICIDES, FUNGICIDES, ANTHELMINTICS, ANTIPROTOZOA AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1990-09-11 | — | — | US | disclosed |
| US-4814332-A | PARASITICIDES | HOFFMAN-LA ROCHE INC. (US) | 1989-03-21 | — | — | US | disclosed |
| EP-0253084-A2 | 1,3-Disubstituted imidazolium salts | F. HOFFMANN-LA ROCHE AG (CH) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | DDT, CYP2E1, CYP1A1 | CLK4 4759/4885ALDH1A1 116/4885KDM4E 1089/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.