Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440860 | 0.91 | NPSR1 (0.59) | SMN1; SMN2NPSR1KDM4CKDM4ELMNA | |
| SCHEMBL7229858 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1KDM4CKDM4ELMNA | |
| SCHEMBL11029352 | 0.81 | KDM4E (0.54) | SMN1; SMN2KDM4ELMNAHAO1ALDH1A1 | |
| SCHEMBL1412516 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2NPSR1KDM4CKDM4ESTAT3 | |
| SCHEMBL31436306 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1KDM4CKDM4ELMNA | |
| SCHEMBL17627087 | 0.77 | SMN1; SMN2 (0.50) | SMN1; SMN2NPSR1KDM4CKDM4ESTAT3 | |
| SCHEMBL1930032 | 0.72 | NPSR1 (0.48) | SMN1; SMN2NPSR1KDM4CKDM4ELMNA | |
| SCHEMBL3033682 | 0.70 | — | — | |
| SCHEMBL5769127 | 0.70 | NPSR1 (0.62) | SMN1; SMN2NPSR1KDM4CKDM4ELMNA | |
| SCHEMBL361255 | 0.70 | KDM4E (0.58) | SMN1; SMN2NPSR1KDM4CKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200239435-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2020-07-30 | — | — | US | disclosed |
| US-10301284-B2 | Therapeutic inhibitory compounds | LIFESCI PHARMACEUTICALS, INC. (BB) | 2019-05-28 | — | — | US | disclosed |
| EP-1539717-A2 | MICROBIOCIDAL (E.G FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | Syngenta Participations AG (CH) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004018438-A2 | MICROBIOCIDAL (E.G. FUNGICIDAL) 1,2,3-TRIAZOLE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200239435-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | KLKB1, SERPINB1, SERPINE1 | SMN1; SMN2 4577/4885NPSR1 1946/4885KDM4C 723/4885 |
| US-10301284-B2 | Therapeutic inhibitory compounds | KLKB1, SERPINB1, SERPINE1 | SMN1; SMN2 4577/4885NPSR1 1946/4885KDM4C 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.