Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832631 | 1.00 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7832049 | 0.88 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL7841727 | 0.88 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL7841141 | 0.88 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL7846948 | 0.86 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL7846131 | 0.86 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL7832463 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7832958 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL7839801 | 0.85 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7833967 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833622-B8 | COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR | SEARLE & CO (US) | 2005-10-12 | — | — | EP | disclosed |
| EP-0833622-A1 | COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR | G.D. SEARLE & CO. (US) | 1998-04-08 | — | — | EP | disclosed |
| WO-1996041626-A1 | COMPOSITIONS COMPRISING A CYCLOOXYGENASE-2 INHIBITOR AND A 5-LIPOXYGENASE INHIBITOR | G.D. SEARLE & CO. (US) | 1996-12-27 | — | — | WO | disclosed |