Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846131 | 1.00 | PTGS2 (0.76) | PTGS2PTGS1 | |
| SCHEMBL7842720 | 0.89 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7844183 | 0.89 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL7841299 | 0.88 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL7843553 | 0.88 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL7840968 | 0.88 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL6440951 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL7832631 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8797155 | 0.86 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL7840136 | 0.85 | PTGS2 (0.72) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1125932-A2 | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 2001-08-22 | — | — | EP | disclosed |
| US-5668161-A | Substituted thiazoles for the treatment of inflammation | G.D. SEARLE & CO. (US) | 1997-09-16 | — | — | US | disclosed |