Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 1/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 2/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.54 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.51 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630664 | 0.85 | ANPEP (0.56) | NR1H3ANPEPDPP4HSPA1APABPC1 | |
| SCHEMBL15323075 | 0.85 | POLB (0.56) | POLBAPAF1NR1H3ESR1ESR2 | |
| SCHEMBL9588487 | 0.83 | NPC1 (0.66) | POLBNR1H3ANPEPDPP4ESR1 | |
| SCHEMBL3373539 | 0.83 | ANPEP (0.54) | NR1H3ANPEPDPP4HSPA1APABPC1 | |
| SCHEMBL887456 | 0.81 | NR1H3 (0.79) | POLBAPAF1NR1H3ESR1ESR2 | |
| SCHEMBL3371679 | 0.81 | ANPEP (0.48) | NR1H3ANPEPDPP4HSPA1APABPC1 | |
| SCHEMBL3373435 | 0.81 | ANPEP (0.48) | NR1H3ANPEPDPP4HSPA1APABPC1 | |
| SCHEMBL3376342 | 0.79 | CCR9 (0.47) | POLBANPEPDPP4HSPA1APABPC1 | |
| SCHEMBL11308425 | 0.79 | KDM4E (0.62) | POLBAPAF1NR1H3ESR1ESR2 | |
| SCHEMBL10792923 | 0.77 | POLB (0.70) | POLBAPAF1NR1H3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1238423-C | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO (JP) | 2006-01-25 | — | — | CN | disclosed |
| US-6956072-B1 | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO., LTD. (JP) | 2005-10-18 | — | — | US | disclosed |
| CN-1361810-A | Thermoplastic resin composition and molded object thereof | POLYPLASTICS CO (JP) | 2002-07-31 | — | — | CN | disclosed |
| US-5246751-A | Poly(hydroxy ether imides) as barrier packaging materials | THE DOW CHEMICAL COMPANY (US) | 1993-09-21 | — | — | US | disclosed |