SCHEMBL9630664

SCHEMBL9630664

O=C1c2cccc(O)c2C(=O)N1c1ccc(Cc2ccc(N3C(=O)c4cccc(O)c4C3=O)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.56
DPP4 P27487 2/20 0.56
NR1H3 Q13133 5/20 0.53
ADORA2A P29274 1/20 0.48
HSPA1A P0DMV8 1/20 0.47
PABPC1 P11940 1/20 0.47
NR1H2 P55055 1/20 0.46
PPARA Q07869 2/20 0.46
PPARD Q03181 1/20 0.46
TYMS P04818 1/20 0.45
AHR P35869 1/20 0.44
MEN1 O00255 1/20 0.43
NPC1 O15118 1/20 0.43
USP2 O75604 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
ATM Q13315 1/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6441097 0.85 POLB (0.58) ANPEPDPP4NR1H3ADORA2AHSPA1A
SCHEMBL9468703 0.83 HSPA1A (0.71) DPP4NR1H3ADORA2AHSPA1APABPC1
SCHEMBL5659843 0.81 PPARA (0.60) ANPEPDPP4NR1H3HSPA1APABPC1
SCHEMBL11849348 0.81 CTDSP1 (0.58) NR1H3ADORA2AHSPA1APABPC1PPARA
SCHEMBL9480783 0.79 NR1H3 (0.66) NR1H3NR1H2PPARAPPARDMEN1
SCHEMBL3373539 0.79 ANPEP (0.54) ANPEPDPP4NR1H3ADORA2AHSPA1A
SCHEMBL15858818 0.79 NR1H3 (0.81) NR1H3NR1H2PPARAPPARDMEN1
SCHEMBL11526483 0.78 MGLL (0.56) NR1H3ADORA2AHSPA1APABPC1PPARA
SCHEMBL3371679 0.77 ANPEP (0.48) ANPEPDPP4NR1H3ADORA2AHSPA1A
SCHEMBL9502422 0.77 KDM4E (0.61) ADORA2AHSPA1APABPC1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195402-B1 BIS(HYDROXYPHTHALIMIDE) AND PROCESS FOR PREPARING THE SAME, AND PROCESS FOR PREPARING POLYESTERIMIDE BY THE USE THEREOF NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1992-06-10 EP disclosed
US-4948831-A MOLDING HEAT RESISTANT MIXTURES NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-08-14 US disclosed
US-4855390-A Process for preparing polyesterimide from bis(hydroxyphthalimide) NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-08-08 US disclosed
US-4808676-A HEAT RESISTANCE, WATERPROOF FILM NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1989-02-28 US disclosed
US-4769475-A Bis(hydroxyphthalimide) and process for preparing the same, and process for preparing polyesterimide by the use thereof NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-09-06 US disclosed
EP-0195402-A2 Bis(hydroxyphthalimide) and process for preparing the same, and process for preparing polyesterimide by the use thereof NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1986-09-24 EP disclosed