Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 6/20 | 0.50 |
| ▸ | CES2 | O00748 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 8/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168785 | 0.75 | — | — | |
| SCHEMBL29977877 | 0.75 | — | — | |
| SCHEMBL9452636 | 0.75 | — | — | |
| SCHEMBL11052413 | 0.75 | CES1 (0.59) | CES1CES2ALDH1A1CA1TP53 | |
| SCHEMBL1311255 | 0.74 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL29943792 | 0.73 | CES1 (0.44) | CES1CES2ALDH1A1CA1TP53 | |
| Octanol SCHEMBL28612657 | 0.72 | ALDH1A1 (0.65) | CES1CES2ALDH1A1PPARGPPARA | |
| Hexane SCHEMBL27687689 | 0.71 | ALDH1A1 (0.57) | CES1CES2ALDH1A1 | |
| Pentane SCHEMBL7754125 | 0.71 | — | — | |
| Hexane SCHEMBL10491880 | 0.71 | ALDH1A1 (0.57) | CES1CES2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3475277-B1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2021-10-20 | — | — | EP | disclosed |
| EP-3475277-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | Bioimics AB (SE) | 2019-05-01 | — | — | EP | disclosed |
| WO-2017222466-A1 | ANTI-INFECTIVE HETEROCYCLIC COMPOUNDS AND USES THEREOF | BIOIMICS AB (SE) | 2017-12-28 | — | — | WO | disclosed |
| EP-0489085-B1 | RIGID-ROD POLYMERS | MISSISSIPPI POLYMER TECHNOLOGI (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20040157919-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | WU YONG-QIAN (US) | 2004-08-12 | — | — | US | disclosed |
| US-6656971-B2 | Non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilins; inhibiting their peptidyl-prolyl isomerase activity; treating variety of medical conditions | GUILFORD PHARMACEUTICALS INC. | 2003-12-02 | — | — | US | disclosed |
| EP-1360173-A2 | TRISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE | GUILFORD PHARMACEUTICALS INC. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020165275-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | GUILFORD PHARMACEUTICALS INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002059080-A2 | TRISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE | GUILFORD PHARMACEUTICALS INC. (US) | 2002-08-01 | — | — | WO | disclosed |
| US-5659005-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1997-08-19 | — | — | US | disclosed |
| US-5565543-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1996-10-15 | — | — | US | disclosed |
| US-5227457-A | Rigid-rod polymers | MAXDEM INCORPORATED (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0489085-A4 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1992-08-05 | — | — | EP | disclosed |
| EP-0489085-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1992-06-10 | — | — | EP | disclosed |
| EP-0401296-A4 | RIGID-ROD POLYMERS | MAXDEM INC (US) | 1992-03-18 | — | — | EP | disclosed |
| WO-1991002764-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1991-03-07 | — | — | WO | disclosed |
| EP-0401296-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1990-12-12 | — | — | EP | disclosed |
| WO-1989007617-A1 | RIGID-ROD POLYMERS | MAXDEM INCORPORATED (US) | 1989-08-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157919-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | FKBP2, PPIG, FKBP8 | CES1 140/4885CES2 559/4885ALDH1A1 2070/4885 |
| US-20020165275-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | FKBP2, PPIG, FKBP8 | CES1 140/4885CES2 559/4885ALDH1A1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.