Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6441614 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDPIK3R1PIK3CA | |
| SCHEMBL6441615 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDPIK3R1PIK3CA | |
| SCHEMBL6441844 | 0.82 | PDE4D (0.36) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6441838 | 0.82 | PDE4D (0.36) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6441834 | 0.82 | PDE4D (0.36) | ALDH1A1KDM4EHPGDMEN1KMT2A | |
| SCHEMBL6442306 | 0.81 | PDE4D (0.37) | KDM4EMEN1KMT2APDE4DPDE4A | |
| SCHEMBL6442302 | 0.81 | PDE4D (0.37) | KDM4EMEN1KMT2APDE4DPDE4A | |
| SCHEMBL6442311 | 0.81 | PDE4D (0.37) | KDM4EMEN1KMT2APDE4DPDE4A | |
| SCHEMBL6442566 | 0.80 | LMNA (0.39) | ALDH1A1KDM4EHPGDKMT2ATP53 | |
| SCHEMBL6442562 | 0.80 | LMNA (0.39) | ALDH1A1KDM4EHPGDKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303506-B1 | 6-HETEROARYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2005-02-02 | — | — | EP | claimed |
| EP-1303506-B1 | 6-HETEROARYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2005-02-02 | — | — | EP | disclosed |