Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609249 | 0.79 | KDM4E (0.47) | KDM4CALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2487118 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL4218051 | 0.71 | KDM4C (0.41) | KDM4CALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6653301 | 0.69 | KDM4E (0.56) | KDM4CALDH1A1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL3720298 | 0.67 | CYP2A6 (0.52) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL5966866 | 0.67 | CCR1 (0.42) | KDM4CALDH1A1 | |
| SCHEMBL3708688 | 0.66 | GPR84 (0.39) | ALDH1A1SMN1; SMN2KDM4ELMNAHPGD | |
| SCHEMBL1988750 | 0.65 | KDM4E (0.58) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8652583 | 0.65 | CYP2A6 (0.50) | ALDH1A1SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL17850816 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3888147-A1 | COMPOUNDS FOR ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2021-10-06 | — | — | EP | disclosed |
| EP-3288938-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016174074-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-03 | — | — | WO | disclosed |
| WO-2013153539-A1 | TRICYCLIC COMPOUNDS AS TEC KINASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-10-17 | — | — | WO | disclosed |
| EP-1561753-A2 | Benzo[b]chromenonapthyridin-7-one and pyrano[2',3':7,8]quino[2,3-b]Quinoxalin-7-one derivatives, process of synthesis, pharmaceutical compositions and their antitumoral properties for the treatment of cancer | Les Laboratoires Servier (FR) | 2005-08-10 | — | — | EP | disclosed |