⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29529148 | 0.86 | KDM4E (0.54) | — | |
| SCHEMBL439769 | 0.86 | KDM4E (0.54) | — | |
| SCHEMBL27768754 | 0.85 | KDM4E (0.52) | — | |
| SCHEMBL2487118 | 0.81 | — | — | |
| Pyridine SCHEMBL28181012 | 0.80 | KDM4C (0.49) | — | |
| SCHEMBL28027112 | 0.76 | FKBP5 (0.53) | — | |
| SCHEMBL11983623 | 0.76 | CCR1 (0.57) | — | |
| SCHEMBL16139800 | 0.76 | KDM4C (0.57) | — | |
| Quinoline SCHEMBL28115235 | 0.74 | ALDH1A1 (0.55) | — | |
| SCHEMBL18204056 | 0.74 | KDM4E (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200015-B1 | SUBSTITUTED HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF TLR9 | BRISTOL MYERS SQUIBB CO (US) | 2026-04-29 | — | — | EP | claimed |
| EP-3564241-B1 | 4H-PYRROLOPYRIDINE COMPOUND OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | NIHON NOHYAKU CO LTD (JP) | 2022-12-14 | — | — | EP | claimed |
| CN-110121500-B | 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same | 日本农药株式会社 | 2022-05-03 | — | — | CN | claimed |
| US-11083198-B2 | 4H-pyrrolopyridine compound or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide | NIHON NOHYAKU CO., LTD. (JP) | 2021-08-10 | — | — | US | claimed |
| US-20200085056-A1 | 4H-PYRROLOPYRIDINE COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO., LTD. (JP) | 2020-03-19 | — | — | US | claimed |
| EP-3564241-A1 | 4H-PYRROLOPYRIDINE COMPOUND OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | Nihon Nohyaku Co., Ltd. (JP) | 2019-11-06 | — | — | EP | claimed |
| US-20230099204-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER IN WHICH KRAS MUTATION AND ACTIVATED RON ARE PRESENT | WELLMARKER BIO CO., LTD. (KR) | 2023-03-30 | — | — | US | disclosed |
| EP-3564241-B1 | 4H-PYRROLOPYRIDINE COMPOUND OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | NIHON NOHYAKU CO LTD (JP) | 2022-12-14 | — | — | EP | disclosed |
| EP-3564241-B1 | 4H-PYRROLOPYRIDINE COMPOUND OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | NIHON NOHYAKU CO LTD (JP) | 2022-12-14 | — | — | EP | disclosed |
| EP-3774755-B1 | SPIROCYCLIC COMPOUNDS AS MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE | PHENEX DISCOVERY VERWALTUNGS GMBH (DE) | 2022-05-18 | — | — | EP | disclosed |
| CN-110121500-B | 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same | 日本农药株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-110121500-B | 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same | 日本农药株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-110121500-B | 4H-pyrrolopyridine compound or salt thereof, agricultural or horticultural insecticide containing same, and method for using same | 日本农药株式会社 | 2022-05-03 | — | — | CN | disclosed |
| WO-2018124128-A1 | 4H-PYRROLOPYRIDINE COMPOUND OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | 日本農薬株式会社 | 2018-07-05 | — | — | WO | disclosed |
| WO-2017174640-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS ANTIVIRAL AGENTS | INNOVATIVES MOLECULES GMBH (DE) | 2017-10-12 | — | — | WO | disclosed |
| EP-3118189-A1 | CARBOXAMIDE OR SULFONAMIDE SUBSTITUTED NITROGEN-CONTAINING 5-MEMBERED HETEROCYCLES AS MODULATORS FOR THE ORPHAN NUCLEAR RECEPTOR ROR GAMMA | Phenex Pharmaceuticals AG (DE) | 2017-01-18 | — | — | EP | disclosed |
| CN-105980400-A | Growth differentiation factor 15(GDF-15) constructs | 美国安进公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-103917529-B | 2-Thiopyrimidinones | 辉瑞大药厂 | 2016-08-17 | — | — | CN | disclosed |
| EP-3034499-A1 | Novel FXR (NR1H4) modulating compounds | Gilead Sciences, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |
| EP-3034501-A1 | Hydroxy containing FXR (NR1H4) modulating compounds | Gilead Sciences, Inc. (US) | 2016-06-22 | — | — | EP | disclosed |