Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596276 | 0.87 | HCAR2 (0.42) | HCAR2KEAP1NFE2L2NPSR1MAPT | |
| SCHEMBL2992531 | 0.79 | HCAR2 (0.34) | HCAR2KEAP1NFE2L2NPSR1 | |
| SCHEMBL1450059 | 0.79 | HCAR2 (0.34) | HCAR2KEAP1NFE2L2NPSR1 | |
| SCHEMBL12026363 | 0.77 | NPSR1 (0.37) | HCAR2KEAP1NFE2L2NPSR1ALDH1A1 | |
| SCHEMBL29367967 | 0.76 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2NPSR1MAPT | |
| SCHEMBL14767817 | 0.76 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL5953576 | 0.76 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2NPSR1MAPT | |
| SCHEMBL14012897 | 0.76 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2MAPTALDH1A1 | |
| SCHEMBL3051884 | 0.76 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2NPSR1MAPT | |
| SCHEMBL3051883 | 0.76 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2NPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6846783-B2 | Acylatign agents and dispersants for lubricating oil and fuels | THE LUBRIZOL CORPORATION (US) | 2005-01-25 | — | — | US | disclosed |
| EP-1303578-A2 | ACYLATING AGENTS AND DISPERSANTS FOR LUBRICATING OIL AND FUELS | THE LUBRIZOL CORPORATION (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2001098439-A2 | ACYLATING AGENTS AND DISPERSANTS FOR LUBRICATING OIL AND FUELS | THE LUBRIZOL CORPORATION (US) | 2001-12-27 | — | — | WO | disclosed |