Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 6/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 4/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4204848 | 0.75 | OPRM1 (0.60) | OPRM1OPRL1OPRD1OPRK1GRIN2B | |
| SCHEMBL4989701 | 0.73 | OPRM1 (0.58) | OPRM1OPRL1OPRD1OPRK1GRIN2B | |
| SCHEMBL17493640 | 0.73 | OPRM1 (0.58) | OPRM1OPRL1OPRD1OPRK1GRIN2B | |
| Hydrochloric Acid SCHEMBL27656058 | 0.72 | OPRM1 (0.59) | OPRM1OPRL1OPRD1OPRK1KDM1A | |
| SCHEMBL6442514 | 0.71 | OPRM1 (0.40) | OPRM1OPRL1OPRD1OPRK1TRPA1 | |
| SCHEMBL28914563 | 0.71 | OPRM1 (0.69) | OPRM1OPRL1HSD17B3OPRD1OPRK1 | |
| SCHEMBL21058267 | 0.71 | KDM1A (0.43) | OPRM1OPRL1OPRK1KDM1AMAOA | |
| SCHEMBL26326653 | 0.65 | CYP2D6 (0.46) | OPRM1GRIN2B | |
| SCHEMBL3088687 | 0.64 | OPRM1 (0.51) | OPRM1OPRL1HSD17B3OPRD1OPRK1 | |
| SCHEMBL5349572 | 0.64 | OPRM1 (0.59) | OPRM1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6887824-B1 | Divalent lanthanide reduction catalysts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-03 | — | — | US | disclosed |