SCHEMBL4989701

SCHEMBL4989701

OC1(CCc2ccccc2)CCCCC1

nearest known ligand 0.58

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.58
OPRL1 P41146 4/20 0.58
OPRD1 P41143 3/20 0.51
OPRK1 P41145 3/20 0.51
TDP1 Q9NUW8 1/20 0.41
SIGMAR1 Q99720 2/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
KDM1A O60341 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
GRIN2B Q13224 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17493640 1.00 OPRM1 (0.58) OPRM1OPRL1OPRD1OPRK1TDP1
Hydrochloric Acid SCHEMBL27656058 0.98 OPRM1 (0.59) OPRM1OPRL1OPRD1OPRK1TDP1
SCHEMBL4204848 0.94 OPRM1 (0.60) OPRM1OPRL1OPRD1OPRK1TDP1
SCHEMBL28914563 0.90 OPRM1 (0.69) OPRM1OPRL1OPRD1OPRK1TDP1
SCHEMBL5349572 0.89 OPRM1 (0.59) OPRM1OPRL1OPRD1OPRK1SIGMAR1
Hydrochloric Acid SCHEMBL27651798 0.84 FFAR1 (0.47) OPRM1OPRL1OPRD1OPRK1
SCHEMBL8023946 0.83 OPRM1 (0.54) OPRM1OPRL1OPRD1OPRK1TDP1
SCHEMBL4270075 0.82 ESR1 (0.48) OPRM1OPRL1TDP1SIGMAR1KMT2A
SCHEMBL3106679 0.82 LTA4H (0.55) OPRM1OPRL1MAOB
SCHEMBL5672427 0.81 OPRM1 (0.55) OPRM1OPRL1OPRD1OPRK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10370767-B2 Process for preparing alcohols by electrochemical reductive coupling BASF SE (DE) 2019-08-06 US disclosed
CN-106574380-B The method for preparing alcohol by electrochemical reduction coupling 巴斯夫欧洲公司 2019-05-07 CN disclosed
EP-3180459-B1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2019-01-09 EP disclosed
US-20170233874-A1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2017-08-17 US disclosed
EP-3180459-A1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2017-06-21 EP disclosed
WO-2016023951-A1 PROCESS FOR PREPARING ALCOHOLS BY ELECTROCHEMICAL REDUCTIVE COUPLING BASF SE (DE) 2016-02-18 WO disclosed
EP-2985364-A1 Process for preparing alcohols by electrochemical reductive coupling BASF SE (DE) 2016-02-17 EP disclosed
US-7345096-B2 Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms WYETH (US) 2008-03-18 US disclosed
US-7273952-B2 Substituted C-cyclohexylmethylamine derivatives GRUENENTHAL GMBH (DE) 2007-09-25 US disclosed
EP-1687288-A1 SUBSTITUTED ARYL CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE Wyeth (US) 2006-08-09 EP disclosed
US-7022739-B2 Substituted 1-aminobutan-3-ol compounds GRUENENTHAL GMBH (DE) 2006-04-04 US disclosed
US-6887824-B1 Divalent lanthanide reduction catalysts THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2005-05-03 US disclosed
WO-2005037809-A1 SUBSTITUTED ARYL CYCLOALKANOL DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2005-04-28 WO disclosed
EP-1242468-A1 DIVALENT LANTHANIDE REDUCTION CATALYSTS The Regents of the University of California (US) 2002-09-25 EP disclosed
WO-2001021667-A1 DIVALENT LANTHANIDE REDUCTION CATALYSTS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-03-29 WO disclosed
US-5962469-A PREVENTION OF OXIDATION TISSUE DAMAGE BY FREE RADICALS HOECHST MARION ROUSSEL INC. (US) 1999-10-05 US disclosed
EP-0863878-A1 CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM HOECHST MARION ROUSSEL, INC. (US) 1998-09-16 EP disclosed
WO-1997010218-A1 CYCLIC NITRONES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM HOECHST MARION ROUSSEL, INC. (US) 1997-03-20 WO disclosed
US-5124415-A Crosslinking setting means; film-forming; for use in high frequency satellite communication bands MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1992-06-23 US disclosed
US-4874826-A CROSSLINKING, COPOLYMERZIATION, FORMING FILMS MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1989-10-17 US disclosed