SCHEMBL644277

SCHEMBL644277

CCOC(=O)C(Cl)(Cl)Cc1ccc(F)c(-n2nc(C)n(C(F)F)c2=O)c1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.40
DHODH Q02127 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL644022 0.88 PPOX (0.44) PPOX
SCHEMBL5970688 0.81 PPOX (0.39) PPOX
Ethyl Propionate SCHEMBL27662818 0.78 PPOX (0.42) PPOX
SCHEMBL28694062 0.77 PPOX (0.43) PPOX
SCHEMBL27388906 0.76 PPOX (0.40) PPOXDHODH
Propionic Acid SCHEMBL27682308 0.75 PPOX (0.45) PPOX
SCHEMBL7938990 0.73 PPOX (0.40) PPOX
SCHEMBL9428380 0.73 PPOX (0.48) PPOX
SCHEMBL30537050 0.73 PPOX (0.47) PPOX
SCHEMBL20267538 0.73 PPOX (0.47) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8252721-B2 Herbicidal compositions ISEM S.R.L. (IT) 2012-08-28 US claimed
US-20100016160-A1 HERBICIDAL COMPOSITIONS ISAGRO S.P.A. (IT) 2010-01-21 US claimed
US-RE38314-E1 Process for the preparation of the herbicide ethyl α-2-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazol-1-yl]-4-fluorobenzenepropanoate FMC CORPORATION 2003-11-11 US claimed
EP-1036068-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF A TRIAZOLINE HERBICIDE FMC CORP (US) 2003-03-12 EP claimed
EP-1273232-A1 Process for the preparation of the herbicide ethyl alpha-2-dichloro-5-[4-(difluoromethyl)-4,5-dihydro-3-methyl-5-oxo-1h-1,2,4-triazol-1-yl]-4-fluorobenzenepropanoate FMC CORPORATION (US) 2003-01-08 EP claimed
JP-2001519418-A 2001-10-23 JP claimed
EP-1036068-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF A TRIAZOLINE HERBICIDE FMC CORPORATION (US) 2000-09-20 EP claimed
US-6077959-A Process for the preparation of a triazolinone herbicide FMC CORPORATION (US) 2000-06-20 US claimed
WO-1999057982-A1 CROP-SAFENED HERBICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-11-18 WO claimed
WO-1999019308-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF A TRIAZOLINE HERBICIDE FMC CORPORATION (US) 1999-04-22 WO claimed
EP-0774904-B1 HERBICIDAL MIXTURES DU PONT (US) 1998-10-14 EP claimed
EP-0848709-A1 PROCESS FOR THE PREPARATION OF THE HERBICIDE ETHYL ALPHA-2-DICHLORO-5-[4-(DIFLUOROMETHYL)-4,5-DIHYDRO-3-METHYL-5-OXO-1H-1,2,4-TRIAZOL-1-YL]-4-FLUOROBENZENEPROPANOATE FMC CORPORATION (US) 1998-06-24 EP claimed
US-5621112-A SIMULTANEOUS DIAZOTIZATION AND ARYLATION OF ETHYL ACRYLATE FMC CORPORATION (US) 1997-04-15 US claimed
WO-1997007107-A1 PROCESS FOR THE PREPARATION OF THE HERBICIDE ETHYL α-2-DICHLORO-5-[4-(DIFLUOROMETHYL)-4,5-DIHYDRO-3-METHYL-5-OXO-1H-1,2,4-TRIAZOL-1-YL]-4-FLUOROBENZENEPROPANOATE FMC CORPORATION (US) 1997-02-27 WO claimed
WO-2024081762-A1 SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES CORTEVA AGRISCIENCE LLC (US) 2024-04-18 WO disclosed
WO-2024031002-A1 (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS CORTEVA AGRISCIENCE LLC (US) 2024-02-08 WO disclosed
US-20210392888-A1 COMPOSITIONS COMPRISING A PYRIDINE CARBOXYLATE HERBICIDE AND PROTOPORPHYRINOGEN OXIDASE (PROTOX) INHIBITOR HERBICIDES CORTEVA AGRISCIENCE LLC (US) 2021-12-23 US disclosed
WO-1996013977-A2 HERBICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-17 WO disclosed
WO-1996003878-A1 HERBICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-02-15 WO disclosed
WO-1995033746-A1 CYCLIC SULFONAMIDE HERBICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-12-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016160-A1 HERBICIDAL COMPOSITIONS DDT, AOX1, AS3MT PPOX 479/4885DHODH 46/4885
US-20210392888-A1 COMPOSITIONS COMPRISING A PYRIDINE CARBOXYLATE HERBICIDE AND PROTOPORPHYRINOGEN OXIDASE (PROTOX) INHIBITOR HERBICIDES PPOX, PAOX, PNPO PPOX 1/4885DHODH 51/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.