SCHEMBL6443353

SCHEMBL6443353

CO[C@H]1C=C[C@@]2(C)[C@@H](CC[C@@H]3[C@@H]2CC[C@]2(C)[C@@H](OC(=O)Oc4ccccc4)CC[C@@H]32)C1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
SRD5A1 P18405 10/20 0.39
SRD5A2 P31213 8/20 0.39
ESR1 P03372 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
MAPT P10636 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6447177 1.00 MEN1 (0.39) MEN1KMT2ASRD5A1SRD5A2ESR1
SCHEMBL6441599 0.91 MEN1 (0.40) MEN1KMT2ASRD5A1SRD5A2TP53
SCHEMBL6443171 0.91 MEN1 (0.40) MEN1KMT2ASRD5A1SRD5A2TP53
SCHEMBL6446938 0.89 MEN1 (0.40) MEN1KMT2ASRD5A1SRD5A2TP53
SCHEMBL6444908 0.89 MEN1 (0.40) MEN1KMT2ASRD5A1SRD5A2TP53
SCHEMBL6442230 0.88 MEN1 (0.39) MEN1KMT2ASRD5A1SRD5A2CYP3A4
SCHEMBL6442484 0.88 MEN1 (0.39) MEN1KMT2ASRD5A1SRD5A2CYP3A4
SCHEMBL6442035 0.84 CYP3A4 (0.41) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL6443299 0.84 CYP3A4 (0.41) MEN1KMT2ATP53CYP3A4MAPT
SCHEMBL6444134 0.83 MEN1 (0.44) MEN1KMT2ASRD5A1SRD5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050159366-A1 Pharmaceutical compositions and treatment methods - 8 BIOVIE INC. 2005-07-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159366-A1 Pharmaceutical compositions and treatment methods - 8 HSD17B7, NR5A1, HSD3B1 MEN1 2269/4885KMT2A 2320/4885SRD5A1 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.