⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5489681 | 0.76 | — | — | |
| SCHEMBL3973741 | 0.76 | — | — | |
| SCHEMBL4358588 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL11691339 | 0.74 | — | — | |
| SCHEMBL1898403 | 0.74 | — | — | |
| SCHEMBL1371480 | 0.74 | — | — | |
| SCHEMBL6968907 | 0.73 | — | — | |
| SCHEMBL11834705 | 0.73 | — | — | |
| SCHEMBL29580458 | 0.72 | — | — | |
| SCHEMBL7494175 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050130941-A1 | Methods of treating alzheimer's disease | PHARMACIA & UPJOHN COMPANY LLC | 2005-06-16 | — | — | US | disclosed |
| EP-1392315-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100410-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-12-19 | — | — | WO | disclosed |
| US-5753652-A | Antiretroviral hydrazine derivatives | NOVARTIS CORPORATION (US) | 1998-05-19 | — | — | US | disclosed |
| EP-0521827-B1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA GEIGY AG (CH) | 1996-09-25 | — | — | EP | disclosed |
| EP-0521827-A1 | Pharmacological active hydrazin derivatives and process for their preparation | CIBA-GEIGY AG (CH) | 1993-01-07 | — | — | EP | disclosed |
| EP-0166692-B1 | SUBSTITUTED AZABICYCLOHEPTANES, THEIR USE, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PROCESS FOR THE PREPARATION OF THE COMPOUNDS | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |
| US-4857660-A | ENZYME INHIBITORS, ANTICANCER AGENTS | CIBA-GEIGY CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4839379-A | AROMATASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1989-06-13 | — | — | US | disclosed |
| EP-0114033-B1 | SUBSTITUTED AZABICYCLOALKANES, THEIR USE, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THESE COMPOUNDS | CIBA-GEIGY AG (CH) | 1988-10-12 | — | — | EP | disclosed |
| US-4764640-A | AROMATOSE INHIBITOR | CIBA-GEIGY CORPORATION (US) | 1988-08-16 | — | — | US | disclosed |
| US-4677129-A | Substituted-3-azabicyclo[3.1.1]heptane-2,4-diones useful for treating hormone-dependent diseases | CIBA-GEIGY CORPORATION (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0166692-A2 | Substituted azabicycloheptanes, their use, pharmaceutical compositions comprising them and process for the preparation of the compounds | CIBA-GEIGY AG (CH) | 1986-01-02 | — | — | EP | disclosed |
| EP-0114033-A1 | Substituted azabicycloalkanes, their use, pharmaceutical preparations containing these compounds and process for preparing these compounds | CIBA-GEIGY AG (CH) | 1984-07-25 | — | — | EP | disclosed |