SCHEMBL6443948

SCHEMBL6443948

CSCCCCCCCCCl

nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.45
TRPA1 O75762 5/20 0.41
TDP1 Q9NUW8 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6445056 1.00
SCHEMBL6443334 1.00
SCHEMBL6446333 0.97
SCHEMBL882218 0.94
SCHEMBL11631811 0.88 TSHR (0.38) TSHRALDH1A1TRPA1TDP1
SCHEMBL7155535 0.83 TRPA1 (0.50) ALDH1A1TRPA1TDP1
SCHEMBL7156742 0.83 TRPA1 (0.50) ALDH1A1TRPA1TDP1
SCHEMBL7155296 0.83 TRPA1 (0.50) ALDH1A1TRPA1TDP1
SCHEMBL7155007 0.83 TRPA1 (0.50) ALDH1A1TRPA1TDP1
SCHEMBL11965847 0.83 TRPA1 (0.50) ALDH1A1TRPA1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6858679-B2 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions FMC CORPORATION (US) 2005-02-22 US disclosed
EP-1028982-B1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORP (US) 2003-10-29 EP disclosed
US-20030153693-A1 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions QUIRK RODERIC PAUL (US) 2003-08-14 US disclosed
US-6605564-B1 Anionic polymerization initiators and salt additives selected from sodium chloride, sodium iodide, potassium chloride, potassium t-butoxide, for increasing the efficiency of reactions between living polymer anions and electrophiles FMC CORPORATION 2003-08-12 US disclosed
US-6545103-B2 Living polymers FMC CORPORATION 2003-04-08 US disclosed
US-20020010082-A1 Compositions providing improved functionalization of terminal anions and processes for improved functionalization of terminal anions FMC CORPORATION 2002-01-24 US disclosed
EP-1028982-A1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORPORATION (US) 2000-08-23 EP disclosed
WO-1999025740-A1 COMPOSITIONS PROVIDING IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS AND PROCESSES FOR IMPROVED FUNCTIONALIZATION OF TERMINAL ANIONS FMC CORPORATION (US) 1999-05-27 WO disclosed