(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL6443985

O=S(=O)(c1ccccc1)c1ccccc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.70
ANXA2 P07355 1/20 0.55
S100A10 P60903 1/20 0.55
MMP3 P08254 1/20 0.47
MMP8 P22894 1/20 0.47
MMP13 P45452 1/20 0.47
ALDH1A1 P00352 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA13 Q8N1Q1 2/20 0.44
TSHR P16473 2/20 0.44
HSD17B10 Q99714 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625568 0.95 HTR6 (0.64) HTR6ANXA2S100A10MMP3MMP8
SCHEMBL10608103 0.93 HTR6 (0.59) HTR6ANXA2S100A10MMP3MMP8
SCHEMBL10948877 0.93 HTR6 (0.59) HTR6ANXA2S100A10MMP3MMP8
SCHEMBL10608105 0.93 HTR6 (0.59) HTR6ANXA2S100A10MMP3MMP8
SCHEMBL9625077 0.89 ANXA2 (0.71) HTR6ANXA2S100A10MMP3MMP8
(Phenylsulfonyl)Benzene SCHEMBL20187590 0.84 HTR6 (0.50) HTR6ANXA2S100A10MMP3MMP8
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.84 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2CA12CA1
(Phenylsulfonyl)Benzene SCHEMBL13735236 0.84 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2CA12CA1
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.84 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2CA12CA1
(Phenylsulfonyl)Benzene SCHEMBL30255 0.84 HTR6 (1.00) HTR6ALDH1A1SMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309632-B1 ALKYLATED ARYL DISULFONIC ACID CATALYSTS FOR CROSSLINKING POLYETHYLENE KING INDUSTRIES INC (US) 2005-04-27 EP disclosed
EP-1309632-A4 ALKYLATED ARYL DISULFONIC ACID CATALYSTS FOR CROSSLINKING POLYETHYLENE KING INDUSTRIES INC (US) 2004-07-28 EP disclosed
EP-1309632-A1 ALKYLATED ARYL DISULFONIC ACID CATALYSTS FOR CROSSLINKING POLYETHYLENE KING INDUSTRIES, INC. (US) 2003-05-14 EP disclosed
US-6395837-B1 USING A DISULFONATE COMPOUND AS CROSSLINKING AGENT KING INDUSTRIES, INC. 2002-05-28 US disclosed
US-20020035215-A1 Alkylated aryl disulfonic acid catalysts for crosslinking polyethylene KING INDUSTRIES, INC. 2002-03-21 US disclosed
WO-2002012355-A1 ALKYLATED ARYL DISULFONIC ACID CATALYSTS FOR CROSSLINKING POLYETHYLENE KING INDUSTRIES, INC. (US) 2002-02-14 WO disclosed
EP-0558178-B1 Magnetically permeable composition and soft magnetic component KUREHA CHEMICAL IND CO LTD (JP) 1997-03-26 EP disclosed
US-5435929-A Nickel-zinc-copper ferrite and polyphenylene sulfide KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-07-25 US disclosed
EP-0558178-A2 Magnetically permeable composition and soft magnetic component KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1993-09-01 EP disclosed