(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL20187590

O=S(=O)(c1ccccc1)c1ccccc1.[O-][S+](c1ccccc1)c1ccccc1.c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.50
ANXA2 P07355 1/20 0.44
S100A10 P60903 1/20 0.44
MMP13 P45452 3/20 0.41
MMP8 P22894 2/20 0.41
MMP3 P08254 1/20 0.41
KDM4E B2RXH2 1/20 0.39
APEX1 P27695 1/20 0.39
SMN1; SMN2 Q16637 2/20 0.38
ALDH1A1 P00352 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
PKM P14618 1/20 0.37
TSHR P16473 1/20 0.37
TYMS P04818 1/20 0.36
KMT2A Q03164 2/20 0.36
HSD11B1 P28845 1/20 0.36
LOX P28300 1/20 0.36
MEN1 O00255 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL11696343 0.89 HTR6 (0.64) HTR6SMN1; SMN2ALDH1A1POLBMAPT
SCHEMBL9625568 0.85 HTR6 (0.64) HTR6ANXA2S100A10MMP13MMP8
(Phenylsulfonyl)Benzene SCHEMBL6443985 0.84 HTR6 (0.70) HTR6ANXA2S100A10MMP13MMP8
(Phenylsulfinyl)Benzene SCHEMBL11246408 0.84 MAOA (0.41) HTR6MMP13MMP8MMP3KDM4E
SCHEMBL10608105 0.82 HTR6 (0.59) HTR6ANXA2S100A10MMP13MMP8
SCHEMBL10608103 0.82 HTR6 (0.59) HTR6ANXA2S100A10MMP13MMP8
SCHEMBL10948877 0.82 HTR6 (0.59) HTR6ANXA2S100A10MMP13MMP8
SCHEMBL17928342 0.81 HTR6 (0.54) HTR6MMP13MMP8MMP3SMN1; SMN2
SCHEMBL8089982 0.81 MAOA (0.43) HTR6MMP13MMP8MMP3SMN1; SMN2
SCHEMBL9275867 0.78 MAOA (0.45) HTR6MMP13MMP8MMP3SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3801886-A1 KITS COMPRISING CONTAINERS WITH AT LEAST ONE SOLID CATALYTICALLY ACTIVE COMPOUND, AND THEIR USES IN SOLID STATE REACTION RD&C Research, Development & Consulting GmbH (AT) 2021-04-14 EP disclosed
WO-2018096066-A1 MECHANOCHEMICAL PROCESS IN A SOLID STATE REACTION RD&C RESEARCH, DEVELOPMENT & CONSULTING GMBH (AT) 2018-05-31 WO disclosed