Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MIF | P14174 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444113 | 1.00 | CYP1A2 (0.71) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL19449690 | 0.85 | CYP1A2 (0.78) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL17560844 | 0.85 | CYP1A2 (0.78) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL29659678 | 0.83 | CYP1A2 (0.76) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL2491390 | 0.83 | CYP1A2 (1.00) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL2491393 | 0.83 | CYP1A2 (1.00) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL2488962 | 0.83 | MIF (0.74) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL2488965 | 0.83 | MIF (0.74) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL28632043 | 0.82 | CYP1A2 (0.73) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A | |
| SCHEMBL17560740 | 0.82 | CYP1A2 (0.73) | CYP1A2KMT2ASMN1; SMN2POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1184412-B1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | BRIDGESTONE CORP (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6822027-B2 | MODIFIED STYRENE-BUTADIENE COPOLYMER RUBBER THAT HAS A TIN ATOM, NATURAL RUBBER OR SYNTHETIC ISOPRENE RUBBERS, AND A HYDRAZIDE COMPOUND. | BRIDGESTONE CORPORATION (JP) | 2004-11-23 | — | — | US | disclosed |
| US-20020049294-A1 | Rubber composition and heavy duty pneumatic tire using the rubber composition | BRIDGESTONE CORPORATION | 2002-04-25 | — | — | US | disclosed |
| EP-1184412-A1 | Rubber composition and heavy duty pneumetic tire using the rubber composition | Bridgestone Corporation (JP) | 2002-03-06 | — | — | EP | disclosed |