Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | MAOA | P21397 | 1/20 | 0.71 |
| ▸ | SCN4A | P35499 | 1/20 | 0.66 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560738 | 1.00 | CYP1A2 (0.73) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL6162208 | 0.95 | SCN4A (0.74) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL17560844 | 0.86 | CYP1A2 (0.78) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL19449690 | 0.86 | CYP1A2 (0.78) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL2491390 | 0.85 | CYP1A2 (1.00) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL2491393 | 0.85 | CYP1A2 (1.00) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL29659678 | 0.85 | CYP1A2 (0.76) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL24211799 | 0.83 | MAOA (0.71) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL2335529 | 0.83 | MAOA (0.71) | CYP1A2KMT2APOLBSMN1; SMN2MAOA | |
| SCHEMBL5614430 | 0.83 | MAOA (1.00) | CYP1A2SMN1; SMN2MAOARAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2017-10-12 | — | — | US | claimed |
| CN-107106524-A | Methods for treating protozoal infections | 尼奥酷里私人有限公司 | 2017-08-29 | — | — | CN | claimed |
| EP-3188722-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | Neoculi Pty Ltd (AU) | 2017-07-12 | — | — | EP | claimed |
| WO-2016033635-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | NEOCULI PTY LTD (AU) | 2016-03-10 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170291886-A1 | METHODS FOR TREATING PROTOZOAN INFECTIONS | DPM1, ABCB11, PIGS | CYP1A2 110/4885KMT2A 2912/4885POLB 3872/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.