Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 15/20 | 0.56 |
| ▸ | ITGAV | P06756 | 15/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440168 | 0.86 | ITGB3 (0.67) | ITGB3ITGAVMAPK1HSD17B10L3MBTL1 | |
| SCHEMBL5029896 | 0.80 | ITGB3 (0.79) | ITGB3ITGAV | |
| SCHEMBL6440635 | 0.78 | ITGB3 (0.55) | ITGB3ITGAVHSD17B10 | |
| SCHEMBL6446498 | 0.78 | ITGB3 (0.46) | ITGB3ITGAVNPC1TP53RAB9A | |
| SCHEMBL6445537 | 0.77 | ITGB3 (0.49) | ITGB3ITGAVMAPK1ALDH1A1TP53 | |
| SCHEMBL5879550 | 0.76 | ITGB3 (0.73) | ITGB3ITGAV | |
| SCHEMBL6445908 | 0.75 | ITGB3 (0.58) | ITGB3ITGAVNPC1TP53RAB9A | |
| SCHEMBL6439601 | 0.74 | ITGB3 (0.54) | ITGB3ITGAVMAPK1NPC1ALDH1A1 | |
| SCHEMBL6439244 | 0.73 | KDM4E (0.42) | MAPK1KDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL6426207 | 0.72 | ITGB3 (0.71) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |