Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.54 |
| ▸ | ITGAV | P06756 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445537 | 0.86 | ITGB3 (0.49) | ITGB3ITGAVMAPK1L3MBTL1POLB | |
| SCHEMBL6440168 | 0.80 | ITGB3 (0.67) | ITGB3ITGAVMAPK1L3MBTL1 | |
| SCHEMBL6439458 | 0.80 | ITGB3 (0.49) | ITGB3ITGAVSMN1; SMN2LMNA | |
| SCHEMBL5025612 | 0.78 | ITGB3 (0.69) | ITGB3ITGAVMAPK1 | |
| SCHEMBL6444182 | 0.74 | ITGB3 (0.56) | ITGB3ITGAVMAPK1L3MBTL1TP53 | |
| SCHEMBL6439244 | 0.73 | KDM4E (0.42) | MAPK1L3MBTL1POLBKMT2ATP53 | |
| SCHEMBL5025650 | 0.69 | ITGB3 (0.62) | ITGB3ITGAVMAPK1L3MBTL1 | |
| SCHEMBL6439156 | 0.68 | LMNA (0.51) | POLBKMT2AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5026385 | 0.67 | ITGB3 (0.76) | ITGB3ITGAVMAPK1 | |
| SCHEMBL6471245 | 0.65 | ITGB3 (0.57) | ITGB3ITGAVMAPK1L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |