Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | AHR | P35869 | 2/20 | 0.34 |
| ▸ | F7 | P08709 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | F3 | P13726 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL643621 | 0.84 | CYP2A6 (0.48) | CYP2A6NR4A2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL2318276 | 0.79 | ESR1 (0.35) | CYP3A4NPC1CYP19A1RAB9A | |
| SCHEMBL756551 | 0.78 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL10501637 | 0.77 | CCR1 (0.31) | CYP2A6 | |
| SCHEMBL643603 | 0.76 | CYP1A2 (0.48) | CYP2A6ALDH1A1AHRKDM4EHSD17B10 | |
| SCHEMBL2252898 | 0.76 | ALDH1A1 (0.48) | CYP2A6ALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL1296866 | 0.76 | CYP1A2 (0.48) | ALDH1A1TSHRCYP3A4TDP1ALOX15 | |
| SCHEMBL8355321 | 0.76 | NOS1 (0.31) | NOS1 | |
| SCHEMBL646094 | 0.76 | CYP2A6 (0.48) | CYP2A6NR4A2ALDH1A1AHRKDM4E | |
| SCHEMBL645977 | 0.76 | CYP2A6 (0.48) | CYP2A6ALDH1A1SMN1; SMN2CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115716849-A | Synthetic method of aryl phosphorus compound | 海南大学 | 2023-02-28 | — | — | CN | claimed |
| US-9382356-B2 | Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those | MITSUI CHEMICALS, INC. (JP) | 2016-07-05 | — | — | US | claimed |
| EP-0279598-B1 | ARYLPIPERAZINYL-ALKYLENE-PHENYL-HETEROCYCLIC COMPOUNDS | PFIZER INC. (US) | 1993-09-15 | — | — | EP | claimed |
| CN-1015627-B | Process for preparing aryl-piperazinyl-alkylene-phenyl-heterocyclic compounds | PHIZER CORP (US) | 1992-02-26 | — | — | CN | claimed |
| EP-0279598-A2 | Arylpiperazinyl-alkylene-phenyl-heterocyclic compounds | PFIZER INC. (US) | 1988-08-24 | — | — | EP | claimed |
| WO-2024147306-A1 | AMIDE COMPOUND AND HARMFUL ARTHROPOD CONTROL COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2024-07-11 | — | — | WO | disclosed |
| EP-4201923-A1 | 5-SUBSTITUTED 2,3-DIHYDROPYRIDIN-4-ONES AND PROCESS FOR PREPARING THE SAME | Karl-Franzens-Universität Graz (AT) | 2023-06-28 | — | — | EP | disclosed |
| CN-115716849-A | Synthetic method of aryl phosphorus compound | 海南大学 | 2023-02-28 | — | — | CN | disclosed |
| US-11478451-B1 | Macrocyclic chlorine substituted indole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2022-10-25 | — | — | US | disclosed |
| US-11447504-B2 | Macrocyclic chlorine substituted indole derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2022-09-20 | — | — | US | disclosed |
| EP-3710449-B1 | MACROCYCLIC FLUORINE SUBSTITUTED INDOLE DERIVATIVES AS MCL-1 INHIBITORS, FOR USE IN THE TREATMENT OF CANCER | BROAD INST INC (US) | 2022-07-06 | — | — | EP | disclosed |
| US-20220149436-A1 | NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY | MITSUBISHI CHEMICAL CORPORATION (JP) | 2022-05-12 | — | — | US | disclosed |
| US-RE30754-E | GRAFTING MONOMERS WITH AMINE-REACTIVE SITES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4225476-A | HOT MELT ADHESIVES, IMIDATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-30 | — | — | US | disclosed |
| US-RE30322-E | Novel elastomeric graft copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-01 | — | — | US | disclosed |
| US-4139537-A | 3-Aryloxy-1-(2- or 4-iminodihydro-1-pyridyl)-2-propanol antiarrhythmic compounds | COOPER LABORATORIES, INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4065613-A | ETHYLENEBRANCHING AGENTSATACTIC, AMORPHOUS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-27 | — | — | US | disclosed |
| US-4017557-A | WIRE JACKETING, HOSE, BELTS, SEALS, GASKETS, LOW PRESSURE TIRES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3976720-A | Polyamide/polyolefin plastic graft copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-24 | — | — | US | disclosed |
| US-3972961-A | Process for the preparation of graft copolymers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11447504-B2 | Macrocyclic chlorine substituted indole derivatives | CCNT2, CCNL2, CCND2 | CYP2A6 655/4885NR4A2 3369/4885ALDH1A1 747/4885 |
| US-11478451-B1 | Macrocyclic chlorine substituted indole derivatives | CCNT2, CCNL2, CCND2 | CYP2A6 655/4885NR4A2 3369/4885ALDH1A1 747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.