SCHEMBL6444223

SCHEMBL6444223

CC(c1ccc(C(=O)O)c(C(C)C(C)(C)C)c1C(=O)O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 2/20 0.36
ALDH1A1 P00352 1/20 0.34
GRM1 Q13255 1/20 0.34
FABP3 P05413 1/20 0.33
FABP4 P15090 1/20 0.33
CYP1A2 P05177 1/20 0.33
ALOX15 P16050 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
RXRB P28702 1/20 0.30
GLRA3 O75311 1/20 0.30
GLRB P48167 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6444165 0.76 ACE2 (0.38) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL6446199 0.74 ACE2 (0.35) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL11216320 0.74 ACE2 (0.39) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL5695480 0.74 ACE2 (0.39) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL21008764 0.73 ACE2 (0.46) ACE2ALDH1A1ALOX15
SCHEMBL27562387 0.71 ALOX15 (0.39) ALDH1A1ALOX15TDP1
SCHEMBL17797821 0.70 ALDH1A1 (0.38) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL6445692 0.70 ACE2 (0.39) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL6132208 0.69 ACE2 (0.36) ACE2ALDH1A1GRM1FABP3FABP4
SCHEMBL6446419 0.69 ACE2 (0.38) ACE2ALDH1A1GRM1FABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP disclosed
EP-1194396-A1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2002-04-10 EP disclosed
WO-2000078704-A1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AKTIENGESELLSCHAFT (DE) 2000-12-28 WO disclosed