Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.59 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326856 | 0.82 | PCSK9 (0.53) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL28310880 | 0.81 | PCSK9 (0.52) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL197196 | 0.81 | PCSK9 (0.60) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL15591225 | 0.80 | PCSK9 (0.51) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL3188837 | 0.79 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL11359663 | 0.79 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL11357896 | 0.79 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL1026027 | 0.79 | PCSK9 (0.50) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL11356121 | 0.76 | PCSK9 (0.47) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E | |
| SCHEMBL26529342 | 0.76 | PCSK9 (0.47) | PCSK9ALDH1A1CYP2A6CYP2A13KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110101862-B | Treatment of cancer with SMAD3 inhibitors | 香港中文大学 | 2022-11-01 | — | — | CN | claimed |
| US-4925901-A | STORAGE STAABILITY, ONIUM ION CATALYST | THE DOW CHEMICAL COMPANY (US) | 1990-05-15 | — | — | US | claimed |
| CN-117342963-B | 1, 4-Dicarbonyl compound, and preparation method and application thereof | 上海予君生物科技发展有限公司 | 2025-06-17 | — | — | CN | disclosed |
| EP-4313308-A1 | TEAD INHIBITORS AND USES THEREOF | Cedilla Therapeutics, Inc. (US) | 2024-02-07 | — | — | EP | disclosed |
| CN-117342963-A | 1, 4-dicarbonyl compound, and preparation method and application thereof | 上海予君生物科技发展有限公司 | 2024-01-05 | — | — | CN | disclosed |
| US-20230303537-A1 | NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF | SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-110101862-B | Treatment of cancer with SMAD3 inhibitors | 香港中文大学 | 2022-11-01 | — | — | CN | disclosed |
| WO-2022204452-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2022-09-29 | — | — | WO | disclosed |
| CN-107428708-B | Benzoxazine low temperature curable compositions | 亨斯迈先进材料美国有限责任公司 | 2021-11-09 | — | — | CN | disclosed |
| US-20200403167-A1 | Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays | NATIONAL SCIENCE FOUNDATION | 2020-12-24 | — | — | US | disclosed |
| EP-0328020-A2 | Use of a catalyst in epoxy compositions | THE DOW CHEMICAL COMPANY (US) | 1989-08-16 | — | — | EP | disclosed |
| EP-0320628-A1 | Substituted furan compounds which are useful in inhibiting lipoxygenase enzymes, particularly 5-lipoxygenase | ABBOTT LABORATORIES (US) | 1989-06-21 | — | — | EP | disclosed |
| WO-1989004299-A1 | FURAN AND PYRROLE CONTAINING LIPOXYGENASE INHIBITING COMPOUNDS | ABBOTT LABORATORIES (US) | 1989-05-18 | — | — | WO | disclosed |
| EP-0303206-A2 | Process for the preparation of pyrroles | BASF Aktiengesellschaft (DE) | 1989-02-15 | — | — | EP | disclosed |
| CN-87105515-A | Derivatives of phenylbutenamide compounds and preparation method thereof | — | 1988-03-23 | — | — | CN | disclosed |
| EP-0125415-B1 | PROCESS FOR THE PRODUCTION OF PYRROLES | BASF Aktiengesellschaft (DE) | 1986-11-26 | — | — | EP | disclosed |
| US-4560769-A | CATALYTIC CYCLIZATION OF AMMONIA OR AMINE WITH BUT-2-ENE-1,4-DIOL | BASF AKTIENGESELLSCHAFT (DE) | 1985-12-24 | — | — | US | disclosed |
| EP-0125415-A1 | Process for the production of pyrroles | BASF Aktiengesellschaft (DE) | 1984-11-21 | — | — | EP | disclosed |
| US-4243795-A | Polyphosphazene copolymers containing N-substituted pyrrole substituents | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200403167-A1 | Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays | DPYD, PAICS, PDCD11 | PCSK9 4736/4885ALDH1A1 1028/4885CYP2A6 2537/4885 |
| US-20230303537-A1 | NITROGEN-CONTAINING COMPOUND, AND ELECTRONIC ELEMENT AND ELECTRONIC DEVICE THEREOF | NPM1, NFE2L2, MNS1 | PCSK9 4756/4885ALDH1A1 2635/4885CYP2A6 2821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.