SCHEMBL6444905

SCHEMBL6444905

C=CCC[Si](C)(C)CC=C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL235272 0.85 TSHR (0.42) TSHRALDH1A1
SCHEMBL8836112 0.85
SCHEMBL31347669 0.80 TSHR (0.46) TSHRALDH1A1
SCHEMBL236587 0.78
SCHEMBL6062803 0.78
SCHEMBL10520356 0.76
SCHEMBL2464542 0.76
SCHEMBL6063130 0.76 TSHR (0.48) TSHRALDH1A1
SCHEMBL7133372 0.74 TSHR (0.33) TSHRALDH1A1
SCHEMBL22336453 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539688-B1 NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES CENTRE NAT RECH SCIENT (FR) 2016-08-10 EP disclosed
EP-1539688-A2 NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES Rhodia Chimie (FR) 2005-06-15 EP disclosed
WO-2004024681-A2 NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES RHODIA CHIMIE (FR) 2004-03-25 WO disclosed