Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302259 | 0.84 | KMT2A (0.77) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL8589869 | 0.81 | MEN1 (0.68) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL693455 | 0.80 | KMT2A (1.00) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL6429647 | 0.80 | CYP3A4 (1.00) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL12793350 | 0.78 | KMT2A (0.77) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL21067983 | 0.78 | KMT2A (0.82) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL5915341 | 0.78 | KMT2A (0.77) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL29941108 | 0.78 | KMT2A (0.82) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL20389408 | 0.78 | KMT2A (0.77) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 | |
| SCHEMBL25442198 | 0.77 | MEN1 (0.70) | MEN1KMT2ASMN1; SMN2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001764-A4 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2005-08-24 | — | — | EP | claimed |
| JP-2002512625-A | — | — | 2002-04-23 | — | — | JP | claimed |
| EP-1001764-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-24 | — | — | EP | claimed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | claimed |
| WO-1998053814-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | claimed |