Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287776 | 0.84 | AKR1C3 (0.66) | AKR1C3AKR1C1 | |
| SCHEMBL6445534 | 0.81 | MEN1 (0.78) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL693455 | 0.81 | KMT2A (1.00) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL1264512 | 0.81 | HDAC6 (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18134604 | 0.81 | MCOLN3 (0.83) | MEN1KMT2ASMN1; SMN2MCOLN3TSHR | |
| SCHEMBL12655865 | 0.80 | MCOLN3 (0.71) | MEN1KMT2ASMN1; SMN2MCOLN3TSHR | |
| SCHEMBL21067983 | 0.79 | KMT2A (0.82) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL13302259 | 0.79 | KMT2A (0.77) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL29941108 | 0.79 | KMT2A (0.82) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL20389408 | 0.79 | KMT2A (0.77) | MEN1KMT2ACYP3A4CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877737-A1 | NOVEL N-(ARYLSULPHONYL)AMINO ACID DERIVATIVES HAVING BRADYKININ RECEPTOR AFFINITY | SANOFI (FR) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997025315-A1 | NOVEL N-(ARYLSULPHONYL)AMINO ACID DERIVATIVES HAVING BRADYKININ RECEPTOR AFFINITY | SANOFI (FR) | 1997-07-17 | — | — | WO | disclosed |