Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.65 |
| ▸ | HTR2C | P28335 | 9/20 | 0.65 |
| ▸ | HTR2A | P28223 | 7/20 | 0.65 |
| ▸ | HTR2B | P41595 | 6/20 | 0.65 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13742241 | 0.80 | HTR2C (0.96) | MAOBHTR2CHTR2AHTR2BMAOA | |
| Hydrochloric Acid SCHEMBL6427590 | 0.78 | HTR2C (1.00) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL20747663 | 0.75 | PTGS2 (0.41) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL21834929 | 0.75 | PTGS2 (0.41) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL2119239 | 0.72 | OPRK1 (0.55) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL9950472 | 0.72 | OPRK1 (0.55) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL11086077 | 0.72 | OPRK1 (0.55) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL6425606 | 0.72 | MAOB (1.00) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL16019175 | 0.72 | MAOB (1.00) | MAOBHTR2CHTR2AHTR2BMAOA | |
| SCHEMBL15542348 | 0.72 | MAOB (1.00) | MAOBHTR2CHTR2AHTR2BMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005007614-A1 | MONOAMINE OXIDASE INHIBITORS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 6011 (US) | 2005-01-27 | — | — | WO | disclosed |