Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445576 | 1.00 | TSHR (0.38) | TSHRPDK2SMN1; SMN2ADORA2B | |
| SCHEMBL6448268 | 0.78 | NPC1 (0.33) | SMN1; SMN2 | |
| SCHEMBL6448270 | 0.78 | NPC1 (0.33) | SMN1; SMN2 | |
| SCHEMBL6447041 | 0.73 | ATM (0.47) | SMN1; SMN2 | |
| SCHEMBL14968260 | 0.71 | TSHR (0.44) | TSHRSMN1; SMN2 | |
| SCHEMBL21033826 | 0.68 | TSHR (0.41) | TSHRSMN1; SMN2 | |
| SCHEMBL28799347 | 0.68 | TSHR (0.32) | TSHRPDK2 | |
| SCHEMBL6448425 | 0.68 | NPC1 (0.32) | SMN1; SMN2 | |
| SCHEMBL6448419 | 0.68 | NPC1 (0.32) | SMN1; SMN2 | |
| SCHEMBL14967385 | 0.67 | TSHR (0.39) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921832-B2 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2005-07-26 | — | — | US | disclosed |
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1422226-A1 | Optically active fluorine-containing compounds and processes for their production | Tosoh Corporation (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | CYP2C19, CYP2F1, CYP2B6 | TSHR 986/4885PDK2 1931/4885SMN1; SMN2 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.