SCHEMBL6448425

SCHEMBL6448425

O=C(O)C1(C(F)(F)F)CO1

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
LMNA P02545 1/20 0.31
FFAR3 O14843 1/20 0.30
LCK P06239 1/20 0.30
FYN P06241 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6448419 1.00 NPC1 (0.32) NPC1GAARAB9ASMN1; SMN2HSD17B10
SCHEMBL16056817 0.77 DGAT1 (0.32)
SCHEMBL30000700 0.75 MEN1 (0.35) NPC1GAARAB9ASMN1; SMN2HSD17B10
SCHEMBL31276810 0.73 MEN1 (0.34) NPC1GAARAB9ASMN1; SMN2HSD17B10
SCHEMBL3664914 0.72 CES1 (0.45) NPC1GAARAB9ASMN1; SMN2HSD17B10
SCHEMBL6448270 0.72 NPC1 (0.33) NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL6448268 0.72 NPC1 (0.33) NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL6445727 0.72 MEN1 (0.44) LMNA
SCHEMBL6445644 0.69 LMNA (0.33) SMN1; SMN2LMNA
SCHEMBL23302243 0.68 SMN1; SMN2 (0.35) NPC1GAARAB9ASMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220166105-A1 LITHIUM SECONDARY BATTERY INCLUDING SEPARATOR WITH CERAMIC LAYER HAVING FIRST CERAMIC PARTICLE BONDED TO SECOND CERAMIC PARTICLE AND MANUFACTURING METHOD THE SAME KIA CORPORATION (KR) 2022-05-26 US claimed
US-20200194760-A1 LITHIUM SECONDARY BATTERY AND MANUFACTURING METHOD THEREOF KIA MOTORS CORPORATION (KR) 2020-06-18 US claimed
US-12170350-B2 Lithium secondary battery including separator with ceramic layer having first ceramic particle bonded to second ceramic particle and manufacturing method the same HYUNDAI MOTOR COMPANY (KR) 2024-12-17 US disclosed
US-20220166105-A1 LITHIUM SECONDARY BATTERY INCLUDING SEPARATOR WITH CERAMIC LAYER HAVING FIRST CERAMIC PARTICLE BONDED TO SECOND CERAMIC PARTICLE AND MANUFACTURING METHOD THE SAME KIA CORPORATION (KR) 2022-05-26 US disclosed
US-11289768-B2 Lithium secondary battery including separator with ceramic layer having first ceramic particle bonded to second ceramic particle and manufacturing method the same HYUNDAI MOTOR COMPANY (KR) 2022-03-29 US disclosed
US-20200194760-A1 LITHIUM SECONDARY BATTERY AND MANUFACTURING METHOD THEREOF KIA MOTORS CORPORATION (KR) 2020-06-18 US disclosed
US-6921832-B2 Optically active fluorine-containing compounds and processes for their production TOSOH CORPORATION (JP) 2005-07-26 US disclosed
US-20040147756-A1 Optically active fluorine-containing compounds and processes for their production TOSOH CORPORATION (JP) 2004-07-29 US disclosed
EP-1422226-A1 Optically active fluorine-containing compounds and processes for their production Tosoh Corporation (JP) 2004-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040147756-A1 Optically active fluorine-containing compounds and processes for their production CYP2C19, CYP2F1, CYP2B6 NPC1 399/4885GAA 3002/4885RAB9A 465/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.