Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158182 | 0.79 | LMNA (0.46) | LMNA | |
| SCHEMBL1675969 | 0.77 | — | — | |
| SCHEMBL14967401 | 0.75 | LMNA (0.46) | TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22473113 | 0.74 | TSHR (0.34) | TSHRLMNA | |
| SCHEMBL14968260 | 0.72 | TSHR (0.44) | TSHRLMNASMN1; SMN2CYP2D6ALDH1A1 | |
| SCHEMBL11073755 | 0.72 | CTSL (0.34) | — | |
| SCHEMBL14968089 | 0.72 | LMNA (0.38) | TSHRLMNAALDH1A1 | |
| SCHEMBL14967585 | 0.72 | CYP4F2 (0.33) | SMN1; SMN2 | |
| SCHEMBL11272047 | 0.71 | NPSR1 (0.43) | TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL27438426 | 0.71 | LMNA (0.39) | TSHRLMNASMN1; SMN2CYP2D6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10301397-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2019-05-28 | — | — | US | disclosed |
| US-20160340447-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2016-11-24 | — | — | US | disclosed |
| US-9458270-B2 | Method for producing polydienes and polydiene copolymers with reduced cold flow | BRIDGESTONE CORPORATION (JP) | 2016-10-04 | — | — | US | disclosed |
| EP-2780177-B1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORP (JP) | 2016-03-23 | — | — | EP | disclosed |
| US-20140296445-A1 | Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow | BRIDGESTONE CORPORATION (JP) | 2014-10-02 | — | — | US | disclosed |
| EP-2780177-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | Bridgestone Corporation (JP) | 2014-09-24 | — | — | EP | disclosed |
| CN-104023996-A | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORP | 2014-09-03 | — | — | CN | disclosed |
| WO-2013075074-A1 | METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW | BRIDGESTONE CORPORATION (JP) | 2013-05-23 | — | — | WO | disclosed |