Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445594 | 0.92 | P2RX7 (0.78) | P2RX7 | |
| Hydrochloric Acid SCHEMBL6443535 | 0.91 | P2RX7 (0.76) | P2RX7 | |
| Hydrochloric Acid SCHEMBL6442248 | 0.89 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL6447012 | 0.89 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL5553070 | 0.89 | P2RX7 (0.82) | P2RX7 | |
| SCHEMBL6428157 | 0.88 | P2RX7 (0.79) | P2RX7 | |
| Hydrochloric Acid SCHEMBL5549966 | 0.88 | P2RX7 (0.80) | P2RX7 | |
| SCHEMBL7079433 | 0.85 | P2RX7 (0.52) | P2RX7 | |
| SCHEMBL7079398 | 0.84 | P2RX7 (0.58) | P2RX7 | |
| SCHEMBL7077714 | 0.84 | P2RX7 (0.51) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599432-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | AstraZeneca AB (SE) | 2005-11-30 | — | — | EP | claimed |
| WO-2004074224-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | claimed |
| EP-1599432-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | AstraZeneca AB (SE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004074224-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |