Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 19/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6446761 | 0.90 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL6428157 | 0.90 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL6445594 | 0.90 | P2RX7 (0.78) | P2RX7 | |
| Hydrochloric Acid SCHEMBL6443535 | 0.89 | P2RX7 (0.76) | P2RX7 | |
| SCHEMBL6445592 | 0.89 | P2RX7 (0.65) | P2RX7 | |
| Hydrochloric Acid SCHEMBL6442248 | 0.87 | P2RX7 (0.63) | P2RX7 | |
| SCHEMBL5553834 | 0.87 | P2RX7 (0.79) | P2RX7 | |
| SCHEMBL7077870 | 0.85 | P2RX7 (0.54) | P2RX7 | |
| SCHEMBL7081904 | 0.84 | P2RX7 (0.56) | P2RX7 | |
| SCHEMBL7077648 | 0.84 | P2RX7 (0.66) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599432-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | AstraZeneca AB (SE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004074224-A1 | ADAMANTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | WO | disclosed |