Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6445727 | 0.79 | MEN1 (0.44) | LMNADGAT1MEN1KMT2A | |
| SCHEMBL6446725 | 0.74 | TDP1 (0.36) | MEN1KMT2A | |
| SCHEMBL6448268 | 0.71 | NPC1 (0.33) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6448270 | 0.71 | NPC1 (0.33) | LMNAALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL13953492 | 0.71 | DGAT1 (0.57) | LMNAALDH1A1SMN1; SMN2EPHX1DGAT1 | |
| SCHEMBL13976334 | 0.71 | EPHX1 (0.34) | LMNAALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL13976947 | 0.71 | EPHX1 (0.34) | LMNAALDH1A1SMN1; SMN2EPHX1 | |
| SCHEMBL6446980 | 0.69 | HTT (0.45) | ALDH1A1EPHX1 | |
| SCHEMBL6448425 | 0.69 | NPC1 (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL6448419 | 0.69 | NPC1 (0.32) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6921832-B2 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2005-07-26 | — | — | US | disclosed |
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | TOSOH CORPORATION (JP) | 2004-07-29 | — | — | US | disclosed |
| EP-1422226-A1 | Optically active fluorine-containing compounds and processes for their production | Tosoh Corporation (JP) | 2004-05-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147756-A1 | Optically active fluorine-containing compounds and processes for their production | CYP2C19, CYP2F1, CYP2B6 | LMNA 3125/4885ALDH1A1 898/4885SMN1; SMN2 3381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.