Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.53 |
| ▸ | DRD1 | P21728 | 4/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484101 | 0.91 | KCNH2 (0.46) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL16491468 | 0.91 | KCNH2 (0.67) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL4806424 | 0.88 | CYP2D6 (0.50) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL17059857 | 0.88 | HRH3 (0.45) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL10654545 | 0.88 | KCNH2 (0.44) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL10651082 | 0.87 | KCNH2 (0.43) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL3226743 | 0.86 | KCNH2 (0.49) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL9812726 | 0.85 | KCNH2 (0.47) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL38660198 | 0.83 | CHRM2 (0.57) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL30143833 | 0.83 | CYP2D6 (0.69) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6465576-B1 | Fluoroelastomer compositions and articles made therefrom | DYNEON LLC | 2002-10-15 | — | — | US | claimed |
| EP-1194462-A1 | FLUOROELASTOMER COMPOSITIONS AND ARTICLES MADE THEREFROM | Dyneon LLC (US) | 2002-04-10 | — | — | EP | claimed |
| WO-2001002448-A1 | FLUOROELASTOMER COMPOSITIONS AND ARTICLES MADE THEREFROM | DYNEON LLC (US) | 2001-01-11 | — | — | WO | claimed |
| EP-4234551-A2 | PYRIDAZINONES AS PARP7 INHIBITORS | Ribon Therapeutics Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| CN-102046601-B | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R TECH UENO LTD | 2014-08-27 | — | — | CN | disclosed |
| CN-102046601-A | Benzene or thiophene derivative and use thereof as VAP-1 inhibitor | R TECH UENO LTD | 2011-05-04 | — | — | CN | disclosed |
| US-7612064-B2 | Sulfopyrroles | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7612064-B2 | Sulfopyrroles | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-03 | — | — | US | disclosed |
| US-7579365-B2 | Indolyl-3-glyoxylic acid derivatives having antitumor action | ZIOPHRAM ONCOLOGY, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080027110-A1 | Indolyl-3-glyoxylic acid derivatives having antitumor action | ASTA MEDICA AKTIENGESELLSCHAFT | 2008-01-31 | — | — | US | disclosed |
| EP-1467974-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS | SOD CONSEILS RECH APPLIC (FR) | 2007-08-15 | — | — | EP | disclosed |
| US-6403852-B1 | CATALYTIC ALKENYLATION OF ALKYL-SUBSTITUTED AROMATIC HYDROCARBON HAVING HYDROGEN ATOM AT ALPHA-POSITION OF SIDE CHAIN THEREOF WITH CONJUGATED DIENE | SUMITOMO CHEMICAL CO., LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-1194462-A1 | FLUOROELASTOMER COMPOSITIONS AND ARTICLES MADE THEREFROM | Dyneon LLC (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001002448-A1 | FLUOROELASTOMER COMPOSITIONS AND ARTICLES MADE THEREFROM | DYNEON LLC (US) | 2001-01-11 | — | — | WO | disclosed |
| EP-0949230-A1 | PROCESSES FOR PRODUCING ALKENYL-SUBSTITUTED AROMATIC HYDROCARBONS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-10-13 | — | — | EP | disclosed |
| EP-0466340-B1 | Curing fluorocarbon elastomers | MINNESOTA MINING & MFG (US) | 1996-12-11 | — | — | EP | disclosed |
| EP-0350693-B1 | Azetidine derivatives, process for their preparation and their use in the regulation of plant growth | BASF AG (DE) | 1994-09-28 | — | — | EP | disclosed |
| US-5319025-A | Curing fluorocarbon elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-06-07 | — | — | US | disclosed |
| EP-0466340-A2 | Curing fluorocarbon elastomers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-15 | — | — | EP | disclosed |
| EP-0140207-A2 | A process for rapidly curing a brominated fluoroelastomer | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080027110-A1 | Indolyl-3-glyoxylic acid derivatives having antitumor action | IDO1, IDO2, TDO2 | CYP2D6 268/4885CYP2C19 533/4885KCNH2 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.