Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.47 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10639573 | 0.86 | MAPT (0.44) | MAPTCSNK2A1CSNK2A2CSNK2BPOLB | |
| SCHEMBL10639584 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL10633457 | 0.83 | MAPT (0.42) | MAPTCSNK2A1CSNK2A2CSNK2BPOLB | |
| SCHEMBL8598047 | 0.74 | GAA (0.63) | MAPTPOLBGAAMEN1KMT2A | |
| SCHEMBL9502744 | 0.74 | NPSR1 (0.53) | MAPTCSNK2A1CSNK2A2CSNK2BPOLB | |
| SCHEMBL10027329 | 0.73 | ADORA3 (0.52) | CSNK2A1PARP1 | |
| SCHEMBL14771418 | 0.73 | MGAM (0.38) | GAA | |
| SCHEMBL15579814 | 0.72 | MAPT (0.47) | MAPTPOLBGAAMEN1KMT2A | |
| SCHEMBL34469196 | 0.72 | MGAM (0.35) | MAPTGAA | |
| SCHEMBL10633154 | 0.71 | MAPT (0.40) | MAPTCSNK2A1CSNK2A2CSNK2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065062-A1 | NOVEL ANTIVIRAL COMPOUNDS | PHARMARESOURCES(SHANGHAI)CO., LTD. (CN) | 2012-05-18 | — | — | WO | disclosed |