Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.40 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4447340 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRNAAANPC1RAB9A | |
| SCHEMBL1562513 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRNAAANPC1RAB9A | |
| SCHEMBL27909025 | 0.99 | ALDH1A1 (0.43) | ALDH1A1TSHRNAAANPC1RAB9A | |
| Methacrylic Acid SCHEMBL28345316 | 0.97 | ALDH1A1 (0.43) | ALDH1A1TSHRNAAANPC1RAB9A | |
| SCHEMBL1130647 | 0.94 | POLB (0.43) | ALDH1A1TSHRNAAAPOLBCNR2 | |
| SCHEMBL2319089 | 0.88 | HPGD (0.40) | ALDH1A1POLBLMNA | |
| SCHEMBL9453824 | 0.86 | THRA (0.42) | ALDH1A1TSHRPRSS1PRSS2PRSS3 | |
| SCHEMBL30505598 | 0.86 | ALDH1A1 (0.35) | ALDH1A1TSHRNAAANPC1RAB9A | |
| SCHEMBL23664923 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NAAANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9340624 | 0.85 | ALDH1A1 (0.49) | ALDH1A1NAAANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1519968-A1 | LOW WATER CONTENT HIGH REFRACTIVE INDEX, FLEXIBLE, POLYMERIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2005-04-06 | — | — | EP | disclosed |
| US-6852793-B2 | Low water content, high refractive index, flexible, polymeric compositions | BAUSCH & LOMB INCORPORATED (US) | 2005-02-08 | — | — | US | disclosed |
| WO-2004000901-A1 | LOW WATER CONTENT HIGH REFRACTIVE INDEX, FLEXIBLE, POLYMERIC COMPOSITIONS | BAUSCH & LOMB INCORPORATED (US) | 2003-12-31 | — | — | WO | disclosed |
| US-20030236375-A1 | Low water content, high refractive index, flexible, polymeric compositions | MEDICIS PHARMACEUTICAL CORPORATION | 2003-12-25 | — | — | US | disclosed |