SCHEMBL6446401

SCHEMBL6446401

O=P(CCc1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.61
GAA P10253 2/20 0.61
MAPT P10636 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
ALPG P10696 1/20 0.61
ALOX12 P18054 1/20 0.61
NPY1R P25929 1/20 0.61
HTT P42858 1/20 0.61
NPY2R P49146 1/20 0.61
KMT2A Q03164 3/20 0.57
MEN1 O00255 2/20 0.57
TSHR P16473 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.52
USP2 O75604 1/20 0.48
CYP2D6 P10635 1/20 0.47
CFTR P13569 1/20 0.46
POLB P06746 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
LMNA P02545 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2381086 0.83 ALDH1A1 (0.77) ALDH1A1GAAMAPTNPSR1ALPG
SCHEMBL18486441 0.82 TSHR (0.53) ALDH1A1GAAMAPTNPSR1ALPG
Water SCHEMBL22228992 0.80 ALDH1A1 (0.74) ALDH1A1GAAMAPTNPSR1ALPG
Hydrogen Peroxide SCHEMBL8527081 0.80 ALDH1A1 (0.82) ALDH1A1GAAMAPTNPSR1ALPG
SCHEMBL31588234 0.79 MMP13 (0.46) ALDH1A1GAAMAPTNPSR1ALPG
SCHEMBL1801537 0.78 ALDH1A1 (0.86) ALDH1A1GAAMAPTNPSR1ALPG
SCHEMBL4162470 0.78 ALDH1A1 (0.95) ALDH1A1GAAMAPTNPSR1ALPG
SCHEMBL31588191 0.78 ALDH1A1 (0.43) ALDH1A1GAAMAPTNPSR1ALPG
Zinc Ion SCHEMBL28535952 0.77 TSHR (0.53) ALDH1A1ALOX12TSHRCYP2D6CFTR
SCHEMBL28538163 0.77 TSHR (0.53) ALDH1A1ALOX12TSHRCYP2D6CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118908996-A A composition containing C (sp2) P bond or C (sp)3) Process for preparing organic phosphine compound of-P bond 烟台大学 2024-11-08 CN disclosed
US-10103401-B2 Polymer electrolyte composition and polymer electrolyte membrane, polymer electrolyte membrane with catalyst layer, membrane electrode assembly, and polymer electrolyte fuel cell each using the same TORAY INDUSTRIES, INC. (JP) 2018-10-16 US disclosed
EP-3131145-B1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME TORAY INDUSTRIES (JP) 2018-09-05 EP disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
EP-3131145-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTROLYTE ASSEMBLY, AND SOLID POLYMER FUEL CELL USING SAME Toray Industries, Inc. (JP) 2017-02-15 EP disclosed
EP-1546077-A2 CHIRAL DIOLS, THEIR MANUFACTURE AND LIGANDS AND CATALYSTS DERIVED THEREFROM Ciba SC Holding AG (CH) 2005-06-29 EP disclosed
WO-2004031109-A2 CHIRAL DIOLS, THEIR MANUFACTURE AND LIGANDS AND CATALYSTS DERIVED THEREFROM CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-04-15 WO disclosed