Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.32 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7630004 | 0.88 | CA12 (0.36) | CA12CA9GRIK1TSHR | |
| SCHEMBL6449857 | 0.84 | EP300 (0.40) | TSHR | |
| SCHEMBL526261 | 0.82 | FFAR3 (0.35) | FFAR3GRIK1GRIK2TSHR | |
| SCHEMBL6663024 | 0.82 | APEX1 (0.39) | TSHR | |
| SCHEMBL6678151 | 0.81 | CA12 (0.31) | CA12CA2CA9 | |
| SCHEMBL8735926 | 0.80 | — | — | |
| SCHEMBL679457 | 0.79 | KDM5A (0.38) | TSHR | |
| SCHEMBL3285603 | 0.76 | CA12 (0.33) | CA12CA2CA9TSHRMAPK1 | |
| SCHEMBL3285600 | 0.76 | CA12 (0.33) | CA12CA2CA9TSHRMAPK1 | |
| SCHEMBL9637609 | 0.75 | ALDH1A1 (0.33) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509568-A1 | RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS | Lanxess Deutschland GmbH (DE) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003099921-A1 | RUBBER MIXTURES CONTAINING QUATERNARY POLYMERS AND POLAR SOFTENING AGENTS | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | WO | disclosed |