Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.34 |
| ▸ | PPARD | Q03181 | 6/20 | 0.34 |
| ▸ | PPARA | Q07869 | 6/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3673099 | 0.86 | APEX1 (0.40) | APEX1CES1CES2ALDH1A1AKR1B1 | |
| SCHEMBL8755479 | 0.85 | AKR1B1 (0.35) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL6446570 | 0.82 | CA12 (0.32) | TSHR | |
| SCHEMBL1772976 | 0.80 | ALDH1A1 (0.45) | APEX1CES1CES2ALDH1A1AKR1B1 | |
| SCHEMBL18613576 | 0.79 | GPR84 (0.47) | APEX1CES1CES2ALDH1A1AKR1B1 | |
| SCHEMBL499598 | 0.79 | GPR84 (0.47) | APEX1CES1CES2ALDH1A1AKR1B1 | |
| SCHEMBL7630004 | 0.78 | CA12 (0.36) | ALDH1A1AKR1B1GPR84PPARGPPARD | |
| SCHEMBL28127565 | 0.76 | CES1 (0.37) | CES1CES2ALDH1A1TP53MEN1 | |
| SCHEMBL6449857 | 0.76 | EP300 (0.40) | ALDH1A1GPR84PPARGPPARDPPARA | |
| SCHEMBL8735926 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446432-A2 | COPOLYMERS CONTAINING FLUORINE, METHOD FOR THE PRODUCTION AND USE THEREOF | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003033557-A2 | COPOLYMERS CONTAINING FLUORINE, METHOD FOR THE PRODUCTION AND USE THEREOF | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-24 | — | — | WO | disclosed |