Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 2/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2026077 | 0.99 | FOLH1 (0.50) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL2026078 | 0.99 | FOLH1 (0.50) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL6446640 | 0.97 | FOLH1 (0.49) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL9450975 | 0.91 | FOLH1 (0.54) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL5347315 | 0.91 | FOLH1 (0.54) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL7588488 | 0.88 | FOLH1 (0.59) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL6446637 | 0.88 | FOLH1 (0.42) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL9115844 | 0.83 | MMP9 (0.43) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL9450999 | 0.83 | FOLH1 (0.50) | FOLH1PPARASLC1A1PPARGMME | |
| SCHEMBL27740201 | 0.80 | SLC1A1 (0.48) | FOLH1PPARASLC1A1SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095009-B1 | A PROCESS FOR THE PREPARATION OF 4-CARBOXY- 5,8,11- TRIS(CARBOXYMETHYL)- 1-PHENYL- 2-OXA- 5,8,11- TRIAZATRIDECAN- 13-OIC ACID | BRACCO IMAGING SPA (IT) | 2005-06-15 | — | — | EP | disclosed |
| US-6162947-A | Process for the preparation of 4-carboxy-5, 8,11-tris (carboxymethyl)-phenyl-2-oxa-5, 8 11-triazatridecan | DIBRA S.P.A. (IT) | 2000-12-19 | — | — | US | disclosed |